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Impact of N-Alkylamino Substituents on Serotonin Receptor (5-HTR) Affinity and Phosphodiesterase 10A (PDE10A) Inhibition of Isoindole-1,3-dione Derivatives.
Czopek A, Partyka A, Bucki A, Pawłowski M, Kołaczkowski M, Siwek A, Głuch-Lutwin M, Koczurkiewicz P, Pękala E, Jaromin A, Tyliszczak B, Wesołowska A, Zagórska A. Czopek A, et al. Among authors: kolaczkowski m. Molecules. 2020 Aug 25;25(17):3868. doi: 10.3390/molecules25173868. Molecules. 2020. PMID: 32854402 Free PMC article.
Novel Aryloxyethyl Derivatives of 1-(1-Benzoylpiperidin-4-yl)methanamine as the Extracellular Regulated Kinases 1/2 (ERK1/2) Phosphorylation-Preferring Serotonin 5-HT1A Receptor-Biased Agonists with Robust Antidepressant-like Activity.
Sniecikowska J, Gluch-Lutwin M, Bucki A, Więckowska A, Siwek A, Jastrzebska-Wiesek M, Partyka A, Wilczyńska D, Pytka K, Pociecha K, Cios A, Wyska E, Wesołowska A, Pawłowski M, Varney MA, Newman-Tancredi A, Kolaczkowski M. Sniecikowska J, et al. Among authors: kolaczkowski m. J Med Chem. 2019 Mar 14;62(5):2750-2771. doi: 10.1021/acs.jmedchem.9b00062. Epub 2019 Mar 2. J Med Chem. 2019. PMID: 30721053
Discovery of Novel pERK1/2- or β-Arrestin-Preferring 5-HT1A Receptor-Biased Agonists: Diversified Therapeutic-like versus Side Effect Profile.
Sniecikowska J, Gluch-Lutwin M, Bucki A, Więckowska A, Siwek A, Jastrzebska-Wiesek M, Partyka A, Wilczyńska D, Pytka K, Latacz G, Przejczowska-Pomierny K, Wyska E, Wesołowska A, Pawłowski M, Newman-Tancredi A, Kolaczkowski M. Sniecikowska J, et al. Among authors: kolaczkowski m. J Med Chem. 2020 Oct 8;63(19):10946-10971. doi: 10.1021/acs.jmedchem.0c00814. Epub 2020 Sep 23. J Med Chem. 2020. PMID: 32883072 Free PMC article.
Synthesis and biological evaluation of 2-fluoro and 3-trifluoromethyl-phenyl-piperazinylalkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione as potential antidepressant agents.
Zagórska A, Bucki A, Kołaczkowski M, Siwek A, Głuch-Lutwin M, Starowicz G, Kazek G, Partyka A, Wesołowska A, Słoczyńska K, Pękala E, Pawłowski M. Zagórska A, et al. Among authors: kolaczkowski m. J Enzyme Inhib Med Chem. 2016;31(sup3):10-24. doi: 10.1080/14756366.2016.1198902. Epub 2016 Jun 29. J Enzyme Inhib Med Chem. 2016. PMID: 27353547
Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity.
Bucki A, Marcinkowska M, Śniecikowska J, Więckowski K, Pawłowski M, Głuch-Lutwin M, Gryboś A, Siwek A, Pytka K, Jastrzębska-Więsek M, Partyka A, Wesołowska A, Mierzejewski P, Kołaczkowski M. Bucki A, et al. Among authors: kolaczkowski m. J Med Chem. 2017 Sep 14;60(17):7483-7501. doi: 10.1021/acs.jmedchem.7b00839. Epub 2017 Aug 18. J Med Chem. 2017. PMID: 28763213
Aminoalkyl Derivatives of 8-Alkoxypurine-2,6-diones: Multifunctional 5-HT1A /5-HT7 Receptor Ligands and PDE Inhibitors with Antidepressant Activity.
Chłoń-Rzepa G, Zagórska A, Żmudzki P, Bucki A, Kołaczkowski M, Partyka A, Wesołowska A, Kazek G, Głuch-Lutwin M, Siwek A, Starowicz G, Pawłowski M. Chłoń-Rzepa G, et al. Among authors: kolaczkowski m. Arch Pharm (Weinheim). 2016 Dec;349(12):889-903. doi: 10.1002/ardp.201600260. Epub 2016 Nov 21. Arch Pharm (Weinheim). 2016. PMID: 27869315
137 results