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Simultaneous inhibition of PI3K and PAK in preclinical models of neurofibromatosis type 2-related schwannomatosis.
Oncogene. 2024 Mar;43(13):921-930. doi: 10.1038/s41388-024-02958-w. Epub 2024 Feb 9.
Oncogene. 2024.
PMID: 38336988
Free PMC article.
Simultaneous Inhibition of PI3K and PAK in Preclinical Models of Neurofibromatosis Type 2-related Schwannomatosis.
Fernandez-Valle C, Nagel A, Huegel J, Petrilli A, Rosario R, Victoria B, Hardin H.
Fernandez-Valle C, et al.
Res Sq [Preprint]. 2023 Oct 16:rs.3.rs-3405297. doi: 10.21203/rs.3.rs-3405297/v1.
Res Sq. 2023.
PMID: 37886501
Free PMC article.
Updated.
Preprint.
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CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells.
Huegel J, Dinh CT, Martinelli M, Bracho O, Rosario R, Hardin H, Estivill M, Griswold A, Gultekin S, Liu XZ, Fernandez-Valle C.
Huegel J, et al.
Oncotarget. 2022 Jul 19;13:890-904. doi: 10.18632/oncotarget.28254. eCollection 2022.
Oncotarget. 2022.
PMID: 35875610
Free PMC article.
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Cotargeting Phosphoinositide 3-Kinase and Focal Adhesion Kinase Pathways Inhibits Proliferation of NF2 Schwannoma Cells.
Hardin HM, Dinh CT, Huegel J, Petrilli AM, Bracho O, Allaf AM, Karajannis MA, Griswold AJ, Ivan ME, Morcos J, Gultekin SH, Telischi FF, Liu XZ, Fernandez-Valle C.
Hardin HM, et al.
Mol Cancer Ther. 2023 Nov 1;22(11):1280-1289. doi: 10.1158/1535-7163.MCT-23-0135.
Mol Cancer Ther. 2023.
PMID: 37527526
Free PMC article.
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Clusters of reaction rates and concentrations in protein networks such as the phosphotransferase system.
Härdin HM, Zagaris A, Willms AR, Westerhoff HV.
Härdin HM, et al.
FEBS J. 2014 Jan;281(2):531-48. doi: 10.1111/febs.12664. Epub 2013 Dec 23.
FEBS J. 2014.
PMID: 24289186
Free article.
Review.
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Simplified yet highly accurate enzyme kinetics for cases of low substrate concentrations.
Härdin HM, Zagaris A, Krab K, Westerhoff HV.
Härdin HM, et al.
FEBS J. 2009 Oct;276(19):5491-506. doi: 10.1111/j.1742-4658.2009.07233.x. Epub 2009 Aug 28.
FEBS J. 2009.
PMID: 19725885
Free article.
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The contributions of BMP4, positive guidance cues, and repulsive molecules to cutaneous nerve formation in the chick hindlimb.
Honig MG, Camilli SJ, Surineni KM, Knight BK, Hardin HM.
Honig MG, et al. Among authors: hardin hm.
Dev Biol. 2005 Jun 1;282(1):257-73. doi: 10.1016/j.ydbio.2005.03.013.
Dev Biol. 2005.
PMID: 15936345
Free article.
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