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Molecular Mechanism of LEDGF/p75 Dimerization.
Lux V, Brouns T, Čermáková K, Srb P, Fábry M, Mádlíková M, Hořejší M, Kukačka Z, Novák P, Kugler M, Brynda J, DeRijck J, Christ F, Debyser Z, Veverka V. Lux V, et al. Structure. 2020 Dec 1;28(12):1288-1299.e7. doi: 10.1016/j.str.2020.08.012. Epub 2020 Sep 17. Structure. 2020. PMID: 32946742 Free article.
A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Cermakova K, Demeulemeester J, Lux V, Nedomova M, Goldman SR, Smith EA, Srb P, Hexnerova R, Fabry M, Madlikova M, Horejsi M, De Rijck J, Debyser Z, Adelman K, Hodges HC, Veverka V. Cermakova K, et al. Among authors: lux v. Science. 2021 Nov 26;374(6571):1113-1121. doi: 10.1126/science.abe2913. Epub 2021 Nov 25. Science. 2021. PMID: 34822292 Free PMC article.
Multivalency of nucleosome recognition by LEDGF.
Koutná E, Lux V, Kouba T, Škerlová J, Nováček J, Srb P, Hexnerová R, Šváchová H, Kukačka Z, Novák P, Fábry M, Poepsel S, Veverka V. Koutná E, et al. Among authors: lux v. Nucleic Acids Res. 2023 Oct 13;51(18):10011-10025. doi: 10.1093/nar/gkad674. Nucleic Acids Res. 2023. PMID: 37615563 Free PMC article.
Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds.
Machara A, Lux V, Kožíšek M, Grantz Šašková K, Štěpánek O, Kotora M, Parkan K, Pávová M, Glass B, Sehr P, Lewis J, Müller B, Kräusslich HG, Konvalinka J. Machara A, et al. Among authors: lux v. J Med Chem. 2016 Jan 28;59(2):545-58. doi: 10.1021/acs.jmedchem.5b01089. Epub 2016 Jan 6. J Med Chem. 2016. PMID: 26685880
An allosteric HTRA1-calpain 2 complex with restricted activation profile.
Rey J, Breiden M, Lux V, Bluemke A, Steindel M, Ripkens K, Möllers B, Bravo Rodriguez K, Boisguerin P, Volkmer R, Mieres-Perez J, Clausen T, Sanchez-Garcia E, Ehrmann M. Rey J, et al. Among authors: lux v. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2113520119. doi: 10.1073/pnas.2113520119. Epub 2022 Mar 29. Proc Natl Acad Sci U S A. 2022. PMID: 35349341 Free PMC article.
Highs and lows: Genetic susceptibility to daily events.
Sicorello M, Dieckmann L, Moser D, Lux V, Luhmann M, Neubauer AB, Schlotz W, Kumsta R. Sicorello M, et al. Among authors: lux v. PLoS One. 2020 Aug 13;15(8):e0237001. doi: 10.1371/journal.pone.0237001. eCollection 2020. PLoS One. 2020. PMID: 32790782 Free PMC article.
33 results