CRH/CRHR1 mediates prenatal synthetic glucocorticoid programming of depression-like behavior across 2 generations.
Xu YJ, Sheng H, Wu TW, Bao QY, Zheng Y, Zhang YM, Gong YX, Lu JQ, You ZD, Xia Y, Ni X.
Xu YJ, et al. Among authors: sheng h.
FASEB J. 2018 Aug;32(8):4258-4269. doi: 10.1096/fj.201700948RR. Epub 2018 Mar 15.
FASEB J. 2018.
PMID: 29543532
Our study indicates that prenatal sGC can cause epigenetic instability, which increases the risk of disease development in the offspring's later life.-Xu, Y.-J., Sheng, H., Wu, T.-W., Bao, Q.-Y., Zheng, Y., Zhang, Y.-M., Gong, Y....
Our study indicates that prenatal sGC can cause epigenetic instability, which increases the risk of disease development in the offspring's l …