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Cutaneous burn injury represents a major risk factor for the development of traumatic ectopic bone formation following blast-related extremity injury.
Bone. 2024 Apr;181:117029. doi: 10.1016/j.bone.2024.117029. Epub 2024 Feb 7.
Bone. 2024.
PMID: 38331307
Tourniquet-induced ischemia creates increased risk of organ dysfunction and mortality following delayed limb amputation.
Rowe CJ, Walsh SA, Dragon AH, Rhodes AM, Pak OL, Ronzier E, Levi B, Potter BK, Spreadborough PJ, Davis TA.
Rowe CJ, et al. Among authors: spreadborough pj.
Injury. 2023 Mar 4:S0020-1383(23)00179-1. doi: 10.1016/j.injury.2023.02.047. Online ahead of print.
Injury. 2023.
PMID: 36906480
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Tourniquet use following blast-associated complex lower limb injury and traumatic amputation promotes end organ dysfunction and amplified heterotopic ossification formation.
Spreadborough PJ, Strong AL, Mares J, Levi B, Davis TA.
Spreadborough PJ, et al.
J Orthop Surg Res. 2022 Sep 19;17(1):422. doi: 10.1186/s13018-022-03321-z.
J Orthop Surg Res. 2022.
PMID: 36123728
Free PMC article.
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BMP Ligand Trap ALK3-Fc Attenuates Osteogenesis and Heterotopic Ossification in Blast-Related Lower Extremity Trauma.
Strong AL, Spreadborough PJ, Dey D, Yang P, Li S, Lee A, Haskins RM, Grimm PD, Kumar R, Bradley MJ, Yu PB, Levi B, Davis TA.
Strong AL, et al. Among authors: spreadborough pj.
Stem Cells Dev. 2021 Jan 15;30(2):91-105. doi: 10.1089/scd.2020.0162. Epub 2020 Dec 24.
Stem Cells Dev. 2021.
PMID: 33256557
Free PMC article.
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The role of neutrophil extracellular traps and TLR signaling in skeletal muscle ischemia reperfusion injury.
Edwards NJ, Hwang C, Marini S, Pagani CA, Spreadborough PJ, Rowe CJ, Yu P, Mei A, Visser N, Li S, Hespe GE, Huber AK, Strong AL, Shelef MA, Knight JS, Davis TA, Levi B.
Edwards NJ, et al. Among authors: spreadborough pj.
FASEB J. 2020 Dec;34(12):15753-15770. doi: 10.1096/fj.202000994RR. Epub 2020 Oct 22.
FASEB J. 2020.
PMID: 33089917
Free PMC article.
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Small molecule inhibition of non-canonical (TAK1-mediated) BMP signaling results in reduced chondrogenic ossification and heterotopic ossification in a rat model of blast-associated combat-related lower limb trauma.
Strong AL, Spreadborough PJ, Pagani CA, Haskins RM, Dey D, Grimm PD, Kaneko K, Marini S, Huber AK, Hwang C, Westover K, Mishina Y, Bradley MJ, Levi B, Davis TA.
Strong AL, et al. Among authors: spreadborough pj.
Bone. 2020 Oct;139:115517. doi: 10.1016/j.bone.2020.115517. Epub 2020 Jul 2.
Bone. 2020.
PMID: 32622875
Free PMC article.
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