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Highly specific intracellular ubiquitination of a small molecule.
bioRxiv [Preprint]. 2024 Jan 28:2024.01.26.577493. doi: 10.1101/2024.01.26.577493.
bioRxiv. 2024.
PMID: 38328167
Free PMC article.
Preprint.
Rational screening for cooperativity in small-molecule inducers of protein-protein associations.
Liu S, Tong B, Mason JW, Ostrem JM, Tutter A, Hua BK, Tang SA, Bonazzi S, Briner K, Berst F, Zécri FJ, Schreiber SL.
Liu S, et al.
bioRxiv [Preprint]. 2023 May 24:2023.05.22.541439. doi: 10.1101/2023.05.22.541439.
bioRxiv. 2023.
PMID: 37292909
Free PMC article.
Updated.
Preprint.
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Rational Screening for Cooperativity in Small-Molecule Inducers of Protein-Protein Associations.
Liu S, Tong B, Mason JW, Ostrem JM, Tutter A, Hua BK, Tang SA, Bonazzi S, Briner K, Berst F, Zécri FJ, Schreiber SL.
Liu S, et al.
J Am Chem Soc. 2023 Oct 25;145(42):23281-23291. doi: 10.1021/jacs.3c08307. Epub 2023 Oct 10.
J Am Chem Soc. 2023.
PMID: 37816014
Free PMC article.
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Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design.
Ostrem JM, Shokat KM.
Ostrem JM, et al.
Nat Rev Drug Discov. 2016 Nov;15(11):771-785. doi: 10.1038/nrd.2016.139. Epub 2016 Jul 29.
Nat Rev Drug Discov. 2016.
PMID: 27469033
Review.
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A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region.
Schroeder CM, Ostrem JM, Hertz NT, Vale RD.
Schroeder CM, et al.
Elife. 2014 Oct 1;3:e03351. doi: 10.7554/eLife.03351.
Elife. 2014.
PMID: 25272277
Free PMC article.
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