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In pursuit of the triple crown: mechanism-based pharmacodynamic modelling for the optimization of three-drug combinations against KPC-producing Klebsiella pneumoniae.
Onufrak NJ, Smith NM, Satlin MJ, Bulitta JB, Tan X, Holden PN, Nation RL, Li J, Forrest A, Tsuji BT, Bulman ZP. Onufrak NJ, et al. Among authors: holden pn. Clin Microbiol Infect. 2020 Sep;26(9):1256.e1-1256.e8. doi: 10.1016/j.cmi.2020.04.034. Epub 2020 May 5. Clin Microbiol Infect. 2020. PMID: 32387437 Free PMC article.
Mechanistic Insights to Combating NDM- and CTX-M-Coproducing Klebsiella pneumoniae by Targeting Cell Wall Synthesis and Outer Membrane Integrity.
Smith NM, Boissonneault KR, Chen L, Petraitis V, Petraitiene R, Tao X, Zhou J, Lang Y, Kavaliauskas P, Bulman ZP, Holden PN, Cha R, Bulitta JB, Kreiswirth BN, Walsh TJ, Tsuji BT. Smith NM, et al. Among authors: holden pn. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0052722. doi: 10.1128/aac.00527-22. Epub 2022 Aug 4. Antimicrob Agents Chemother. 2022. PMID: 35924913 Free PMC article.
Front-loaded linezolid regimens result in increased killing and suppression of the accessory gene regulator system of Staphylococcus aureus.
Tsuji BT, Brown T, Parasrampuria R, Brazeau DA, Forrest A, Kelchlin PA, Holden PN, Peloquin CA, Hanna D, Bulitta JB. Tsuji BT, et al. Among authors: holden pn. Antimicrob Agents Chemother. 2012 Jul;56(7):3712-9. doi: 10.1128/AAC.05453-11. Epub 2012 Apr 23. Antimicrob Agents Chemother. 2012. PMID: 22526313 Free PMC article.
27 results