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Brain properties predict proximity to symptom onset in sporadic Alzheimer's disease.
Vogel JW, Vachon-Presseau E, Pichet Binette A, Tam A, Orban P, La Joie R, Savard M, Picard C, Poirier J, Bellec P, Breitner JCS, Villeneuve S; Alzheimer’s Disease Neuroimaging Initiative* and the PREVENT-AD Research Group. Vogel JW, et al. Among authors: pichet binette a. Brain. 2018 Jun 1;141(6):1871-1883. doi: 10.1093/brain/awy093. Brain. 2018. PMID: 29688388 Free PMC article.
Plasma p-tau231, p-tau181, PET Biomarkers, and Cognitive Change in Older Adults.
Meyer PF, Ashton NJ, Karikari TK, Strikwerda-Brown C, Köbe T, Gonneaud J, Pichet Binette A, Ozlen H, Yakoub Y, Simrén J, Pannee J, Lantero-Rodriguez J, Labonté A, Baker SL, Schöll M, Vanmechelen E, Breitner JCS, Zetterberg H, Blennow K, Poirier J, Villeneuve S; Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer Disease (PREVENT-AD) Research Group. Meyer PF, et al. Among authors: pichet binette a. Ann Neurol. 2022 Apr;91(4):548-560. doi: 10.1002/ana.26308. Epub 2022 Feb 18. Ann Neurol. 2022. PMID: 35084051
Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer's disease.
Pichet Binette A, Franzmeier N, Spotorno N, Ewers M, Brendel M, Biel D; Alzheimer’s Disease Neuroimaging Initiative; Strandberg O, Janelidze S, Palmqvist S, Mattsson-Carlgren N, Smith R, Stomrud E, Ossenkoppele R, Hansson O. Pichet Binette A, et al. Nat Commun. 2022 Nov 4;13(1):6635. doi: 10.1038/s41467-022-34129-4. Nat Commun. 2022. PMID: 36333294 Free PMC article.
Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline.
Ossenkoppele R, Pichet Binette A, Groot C, Smith R, Strandberg O, Palmqvist S, Stomrud E, Tideman P, Ohlsson T, Jögi J, Johnson K, Sperling R, Dore V, Masters CL, Rowe C, Visser D, van Berckel BNM, van der Flier WM, Baker S, Jagust WJ, Wiste HJ, Petersen RC, Jack CR Jr, Hansson O. Ossenkoppele R, et al. Among authors: pichet binette a. Nat Med. 2022 Nov;28(11):2381-2387. doi: 10.1038/s41591-022-02049-x. Epub 2022 Nov 10. Nat Med. 2022. PMID: 36357681 Free PMC article.
Tau-PET is superior to phospho-tau when predicting cognitive decline in symptomatic AD patients.
Smith R, Cullen NC, Pichet Binette A, Leuzy A, Blennow K, Zetterberg H, Klein G, Borroni E, Ossenkoppele R, Janelidze S, Palmqvist S, Mattsson-Carlgren N, Stomrud E, Hansson O; Alzheimer's Disease Neuroimaging Initiative. Smith R, et al. Among authors: pichet binette a. Alzheimers Dement. 2023 Jun;19(6):2497-2507. doi: 10.1002/alz.12875. Epub 2022 Dec 14. Alzheimers Dement. 2023. PMID: 36516028
Age-related and amyloid-beta-independent tau deposition and its downstream effects.
Wuestefeld A, Pichet Binette A, Berron D, Spotorno N, van Westen D, Stomrud E, Mattsson-Carlgren N, Strandberg O, Smith R, Palmqvist S, Glenn T, Moes S, Honer M, Arfanakis K, Barnes LL, Bennett DA, Schneider JA, Wisse LEM, Hansson O. Wuestefeld A, et al. Among authors: pichet binette a. Brain. 2023 Aug 1;146(8):3192-3205. doi: 10.1093/brain/awad135. Brain. 2023. PMID: 37082959 Free PMC article.
35 results