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Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability.
Goldberg SD, Satomaa T, Aina O, Aitio O, Burke K, Dudkin V, Geist B, Irrechukwu O, Hänninen AL, Heiskanen A, Helin J, Hiltunen JO, Kinyamu-Akunda J, Klein DM, Kohli N, Kotiranta T, Lähteenmäki T, Niemelä R, Pitkänen V, Pynnönen H, Rittase W, Wiley K, Zhou J, Saarinen J. Goldberg SD, et al. Among authors: saarinen j. Mol Cancer Ther. 2024 Feb 7. doi: 10.1158/1535-7163.MCT-23-0591. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38324296
N-glycolylneuraminic acid xenoantigen contamination of human embryonic and mesenchymal stem cells is substantially reversible.
Heiskanen A, Satomaa T, Tiitinen S, Laitinen A, Mannelin S, Impola U, Mikkola M, Olsson C, Miller-Podraza H, Blomqvist M, Olonen A, Salo H, Lehenkari P, Tuuri T, Otonkoski T, Natunen J, Saarinen J, Laine J. Heiskanen A, et al. Among authors: saarinen j. Stem Cells. 2007 Jan;25(1):197-202. doi: 10.1634/stemcells.2006-0444. Epub 2006 Sep 28. Stem Cells. 2007. PMID: 17008421
Glycomics of bone marrow-derived mesenchymal stem cells can be used to evaluate their cellular differentiation stage.
Heiskanen A, Hirvonen T, Salo H, Impola U, Olonen A, Laitinen A, Tiitinen S, Natunen S, Aitio O, Miller-Podraza H, Wuhrer M, Deelder AM, Natunen J, Laine J, Lehenkari P, Saarinen J, Satomaa T, Valmu L. Heiskanen A, et al. Among authors: saarinen j. Glycoconj J. 2009 Apr;26(3):367-84. doi: 10.1007/s10719-008-9217-6. Epub 2008 Nov 27. Glycoconj J. 2009. PMID: 19037724
The N-glycome of human embryonic stem cells.
Satomaa T, Heiskanen A, Mikkola M, Olsson C, Blomqvist M, Tiittanen M, Jaatinen T, Aitio O, Olonen A, Helin J, Hiltunen J, Natunen J, Tuuri T, Otonkoski T, Saarinen J, Laine J. Satomaa T, et al. Among authors: saarinen j. BMC Cell Biol. 2009 Jun 2;10:42. doi: 10.1186/1471-2121-10-42. BMC Cell Biol. 2009. PMID: 19490625 Free PMC article.
N-glycomic profiling as a tool to separate rectal adenomas from carcinomas.
Kaprio T, Satomaa T, Heiskanen A, Hokke CH, Deelder AM, Mustonen H, Hagström J, Carpen O, Saarinen J, Haglund C. Kaprio T, et al. Among authors: saarinen j. Mol Cell Proteomics. 2015 Feb;14(2):277-88. doi: 10.1074/mcp.M114.041632. Epub 2014 Dec 1. Mol Cell Proteomics. 2015. PMID: 25452313 Free PMC article.
Enabling Low Cost Biopharmaceuticals: A Systematic Approach to Delete Proteases from a Well-Known Protein Production Host Trichoderma reesei.
Landowski CP, Huuskonen A, Wahl R, Westerholm-Parvinen A, Kanerva A, Hänninen AL, Salovuori N, Penttilä M, Natunen J, Ostermeier C, Helk B, Saarinen J, Saloheimo M. Landowski CP, et al. Among authors: saarinen j. PLoS One. 2015 Aug 26;10(8):e0134723. doi: 10.1371/journal.pone.0134723. eCollection 2015. PLoS One. 2015. PMID: 26309247 Free PMC article.
234 results