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Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability.
Goldberg SD, Satomaa T, Aina O, Aitio O, Burke K, Dudkin V, Geist B, Irrechukwu O, Hänninen AL, Heiskanen A, Helin J, Hiltunen JO, Kinyamu-Akunda J, Klein DM, Kohli N, Kotiranta T, Lähteenmäki T, Niemelä R, Pitkänen V, Pynnönen H, Rittase W, Wiley K, Zhou J, Saarinen J. Goldberg SD, et al. Among authors: hanninen al. Mol Cancer Ther. 2024 Feb 7. doi: 10.1158/1535-7163.MCT-23-0591. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38324296
Targeting CD33+ acute myeloid leukemia with GLK-33, a lintuzumab-auristatin conjugate with a wide therapeutic window.
Satomaa T, Pynnönen H, Aitio O, Hiltunen JO, Pitkänen V, Lähteenmäki T, Kotiranta T, Heiskanen A, Hänninen AL, Niemelä R, Helin J, Kuusanmaki H, Vänttinen I, Rathod R, Nieminen AI, Yatkin E, Heckman CA, Kontro M, Saarinen J. Satomaa T, et al. Among authors: hanninen al. Mol Cancer Ther. 2024 Apr 2. doi: 10.1158/1535-7163.MCT-23-0720. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38561023
Enabling Low Cost Biopharmaceuticals: A Systematic Approach to Delete Proteases from a Well-Known Protein Production Host Trichoderma reesei.
Landowski CP, Huuskonen A, Wahl R, Westerholm-Parvinen A, Kanerva A, Hänninen AL, Salovuori N, Penttilä M, Natunen J, Ostermeier C, Helk B, Saarinen J, Saloheimo M. Landowski CP, et al. Among authors: hanninen al. PLoS One. 2015 Aug 26;10(8):e0134723. doi: 10.1371/journal.pone.0134723. eCollection 2015. PLoS One. 2015. PMID: 26309247 Free PMC article.
17 results