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Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains.
Zwick RK, Kasparek P, Palikuqi B, Viragova S, Weichselbaum L, McGinnis CS, McKinley KL, Rathnayake A, Vaka D, Nguyen V, Trentesaux C, Reyes E, Gupta AR, Gartner ZJ, Locksley RM, Gardner JM, Itzkovitz S, Boffelli D, Klein OD. Zwick RK, et al. Among authors: gardner jm. Nat Cell Biol. 2024 Feb;26(2):250-262. doi: 10.1038/s41556-023-01337-z. Epub 2024 Feb 6. Nat Cell Biol. 2024. PMID: 38321203
A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance.
Warshauer JT, Belk JA, Chan AY, Wang J, Gupta AR, Shi Q, Skartsis N, Peng Y, Phipps JD, Acenas D, Smith JA, Tamaki SJ, Tang Q, Gardner JM, Satpathy AT, Anderson MS. Warshauer JT, et al. Among authors: gardner jm. J Exp Med. 2021 Aug 2;218(8):e20210759. doi: 10.1084/jem.20210759. Epub 2021 Jun 11. J Exp Med. 2021. PMID: 34115115 Free PMC article.
Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium.
Wang J, Lareau CA, Bautista JL, Gupta AR, Sandor K, Germino J, Yin Y, Arvedson MP, Reeder GC, Cramer NT, Xie F, Ntranos V, Satpathy AT, Anderson MS, Gardner JM. Wang J, et al. Among authors: gardner jm. Sci Immunol. 2021 Nov 12;6(65):eabl5053. doi: 10.1126/sciimmunol.abl5053. Epub 2021 Nov 12. Sci Immunol. 2021. PMID: 34767455 Free PMC article.
A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation.
Kedmi R, Najar TA, Mesa KR, Grayson A, Kroehling L, Hao Y, Hao S, Pokrovskii M, Xu M, Talbot J, Wang J, Germino J, Lareau CA, Satpathy AT, Anderson MS, Laufer TM, Aifantis I, Bartleson JM, Allen PM, Paidassi H, Gardner JM, Stoeckius M, Littman DR. Kedmi R, et al. Among authors: gardner jm. Nature. 2022 Oct;610(7933):737-743. doi: 10.1038/s41586-022-05089-y. Epub 2022 Sep 7. Nature. 2022. PMID: 36071167 Free PMC article.
400 results