Ueyama M - Search Results

1

Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD.

Ueda T, Takeuchi T, Fujikake N, Suzuki M, Minakawa EN, Ueyama M, Fujino Y, Kimura N, Nagano S, Yokoseki A, Onodera O, Mochizuki H, Mizuno T, Wada K, Nagai Y. Ueda T, et al. Among authors: ueyama m. Acta Neuropathol Commun. 2024 Feb 4;12(1):20. doi: 10.1186/s40478-024-01729-8. Acta Neuropathol Commun. 2024. PMID: 38311779 Free PMC article.

2

Therapeutic reduction of GGGGCC repeat RNA levels by hnRNPA3 suppresses neurodegeneration in Drosophila models of C9orf72-linked ALS/FTD.

Taminato T, Takeuchi T, Ueyama M, Mori K, Ikeda M, Mochizuki H, Nagai Y. Taminato T, et al. Among authors: ueyama m. Hum Mol Genet. 2023 May 5;32(10):1673-1682. doi: 10.1093/hmg/ddac298. Hum Mol Genet. 2023. PMID: 36611007

3

FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD.

Fujino Y, Ueyama M, Ishiguro T, Ozawa D, Ito H, Sugiki T, Murata A, Ishiguro A, Gendron T, Mori K, Tokuda E, Taminato T, Konno T, Koyama A, Kawabe Y, Takeuchi T, Furukawa Y, Fujiwara T, Ikeda M, Mizuno T, Mochizuki H, Mizusawa H, Wada K, Ishikawa K, Onodera O, Nakatani K, Petrucelli L, Taguchi H, Nagai Y. Fujino Y, et al. Among authors: ueyama m. Elife. 2023 Jul 18;12:RP84338. doi: 10.7554/eLife.84338. Elife. 2023. PMID: 37461319 Free PMC article.

4

Repeat Expansion Disease Models.

Ueyama M, Nagai Y. Ueyama M, et al. Adv Exp Med Biol. 2018;1076:63-78. doi: 10.1007/978-981-13-0529-0_5. Adv Exp Med Biol. 2018. PMID: 29951815 Review.

5

E46K mutant α-synuclein is more degradation resistant and exhibits greater toxic effects than wild-type α-synuclein in Drosophila models of Parkinson's disease.

Sakai R, Suzuki M, Ueyama M, Takeuchi T, Minakawa EN, Hayakawa H, Baba K, Mochizuki H, Nagai Y. Sakai R, et al. Among authors: ueyama m. PLoS One. 2019 Jun 26;14(6):e0218261. doi: 10.1371/journal.pone.0218261. eCollection 2019. PLoS One. 2019. PMID: 31242217 Free PMC article.

6

Identification of ter94, Drosophila VCP, as a strong modulator of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.

Azuma Y, Tokuda T, Shimamura M, Kyotani A, Sasayama H, Yoshida T, Mizuta I, Mizuno T, Nakagawa M, Fujikake N, Ueyama M, Nagai Y, Yamaguchi M. Azuma Y, et al. Among authors: ueyama m. Hum Mol Genet. 2014 Jul 1;23(13):3467-80. doi: 10.1093/hmg/ddu055. Epub 2014 Feb 4. Hum Mol Genet. 2014. PMID: 24497576

7

p62 plays a protective role in the autophagic degradation of polyglutamine protein oligomers in polyglutamine disease model flies.

Saitoh Y, Fujikake N, Okamoto Y, Popiel HA, Hatanaka Y, Ueyama M, Suzuki M, Gaumer S, Murata M, Wada K, Nagai Y. Saitoh Y, et al. Among authors: ueyama m. J Biol Chem. 2015 Jan 16;290(3):1442-53. doi: 10.1074/jbc.M114.590281. Epub 2014 Dec 5. J Biol Chem. 2015. PMID: 25480790 Free PMC article.

8

Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31.

Ishiguro T, Sato N, Ueyama M, Fujikake N, Sellier C, Kanegami A, Tokuda E, Zamiri B, Gall-Duncan T, Mirceta M, Furukawa Y, Yokota T, Wada K, Taylor JP, Pearson CE, Charlet-Berguerand N, Mizusawa H, Nagai Y, Ishikawa K. Ishiguro T, et al. Among authors: ueyama m. Neuron. 2017 Apr 5;94(1):108-124.e7. doi: 10.1016/j.neuron.2017.02.046. Epub 2017 Mar 23. Neuron. 2017. PMID: 28343865 Free PMC article.

9

NPM-hMLF1 fusion protein suppresses defects of a Drosophila FTLD model expressing the human FUS gene.

Yamamoto I, Azuma Y, Kushimura Y, Yoshida H, Mizuta I, Mizuno T, Ueyama M, Nagai Y, Tokuda T, Yamaguchi M. Yamamoto I, et al. Among authors: ueyama m. Sci Rep. 2018 Jul 26;8(1):11291. doi: 10.1038/s41598-018-29716-9. Sci Rep. 2018. PMID: 30050143 Free PMC article.

10

Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.

Azuma Y, Tokuda T, Kushimura Y, Yamamoto I, Mizuta I, Mizuno T, Nakagawa M, Ueyama M, Nagai Y, Iwasaki Y, Yoshida M, Pan D, Yoshida H, Yamaguchi M. Azuma Y, et al. Among authors: ueyama m. Exp Cell Res. 2018 Oct 15;371(2):311-321. doi: 10.1016/j.yexcr.2018.08.001. Epub 2018 Aug 6. Exp Cell Res. 2018. PMID: 30092221

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