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Targeting the ACOD1-itaconate axis stabilizes atherosclerotic plaques.
Harber KJ, Neele AE, van Roomen CP, Gijbels MJ, Beckers L, Toom MD, Schomakers BV, Heister DA, Willemsen L, Griffith GR, de Goede KE, van Dierendonck XA, Reiche ME, Poli A, L-H Mogensen F, Michelucci A, Verberk SG, de Vries H, van Weeghel M, Van den Bossche J, de Winther MP. Harber KJ, et al. Among authors: van weeghel m. Redox Biol. 2024 Apr;70:103054. doi: 10.1016/j.redox.2024.103054. Epub 2024 Jan 22. Redox Biol. 2024. PMID: 38309122 Free PMC article.
Fasting-induced myocardial lipid accumulation in long-chain acyl-CoA dehydrogenase knockout mice is accompanied by impaired left ventricular function.
Bakermans AJ, Geraedts TR, van Weeghel M, Denis S, João Ferraz M, Aerts JM, Aten J, Nicolay K, Houten SM, Prompers JJ. Bakermans AJ, et al. Among authors: van weeghel m. Circ Cardiovasc Imaging. 2011 Sep;4(5):558-65. doi: 10.1161/CIRCIMAGING.111.963751. Epub 2011 Jul 7. Circ Cardiovasc Imaging. 2011. PMID: 21737602
Mitochondrial long chain fatty acid beta-oxidation in man and mouse.
Chegary M, Brinke Ht, Ruiter JP, Wijburg FA, Stoll MS, Minkler PE, van Weeghel M, Schulz H, Hoppel CL, Wanders RJ, Houten SM. Chegary M, et al. Among authors: van weeghel m. Biochim Biophys Acta. 2009 Aug;1791(8):806-15. doi: 10.1016/j.bbalip.2009.05.006. Epub 2009 May 22. Biochim Biophys Acta. 2009. PMID: 19465148 Free PMC article.
Disease progression in women with X-linked adrenoleukodystrophy is slow.
Huffnagel IC, Dijkgraaf MGW, Janssens GE, van Weeghel M, van Geel BM, Poll-The BT, Kemp S, Engelen M. Huffnagel IC, et al. Among authors: van weeghel m, van geel bm. Orphanet J Rare Dis. 2019 Feb 7;14(1):30. doi: 10.1186/s13023-019-1008-6. Orphanet J Rare Dis. 2019. PMID: 30732635 Free PMC article.
Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B.
van Weeghel M, Abdurrachim D, Nederlof R, Argmann CA, Houtkooper RH, Hagen J, Nabben M, Denis S, Ciapaite J, Kolwicz SC Jr, Lopaschuk GD, Auwerx J, Nicolay K, Des Rosiers C, Wanders RJ, Zuurbier CJ, Prompers JJ, Houten SM. van Weeghel M, et al. Cardiovasc Res. 2018 Aug 1;114(10):1324-1334. doi: 10.1093/cvr/cvy089. Cardiovasc Res. 2018. PMID: 29635338
Modeling Meets Metabolomics-The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism Caenorhabditis elegans.
Witting M, Hastings J, Rodriguez N, Joshi CJ, Hattwell JPN, Ebert PR, van Weeghel M, Gao AW, Wakelam MJO, Houtkooper RH, Mains A, Le Novère N, Sadykoff S, Schroeder F, Lewis NE, Schirra HJ, Kaleta C, Casanueva O. Witting M, et al. Among authors: van weeghel m. Front Mol Biosci. 2018 Nov 14;5:96. doi: 10.3389/fmolb.2018.00096. eCollection 2018. Front Mol Biosci. 2018. PMID: 30488036 Free PMC article.
Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism.
Koenis DS, Medzikovic L, van Loenen PB, van Weeghel M, Huveneers S, Vos M, Evers-van Gogh IJ, Van den Bossche J, Speijer D, Kim Y, Wessels L, Zelcer N, Zwart W, Kalkhoven E, de Vries CJ. Koenis DS, et al. Among authors: van weeghel m, van den bossche j, van loenen pb. Cell Rep. 2018 Aug 21;24(8):2127-2140.e7. doi: 10.1016/j.celrep.2018.07.065. Cell Rep. 2018. PMID: 30134173 Free PMC article.
96 results