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Involvement of BCR::ABL1 in laminin adhesion of Philadelphia chromosome-positive  acute lymphoblastic leukemia through upregulation of integrin α6.
Takahashi K, Nguyen TTT, Watanabe A, Sato H, Saito K, Tamai M, Harama D, Kasai S, Akahane K, Goi K, Kagami K, Abe M, Komatsu C, Maeda Y, Sugita K, Inukai T. Takahashi K, et al. Among authors: harama d. Cancer Rep (Hoboken). 2024 Apr;7(4):e2034. doi: 10.1002/cnr2.2034. Cancer Rep (Hoboken). 2024. PMID: 38577721 Free PMC article.
Influence of household pet ownership and filaggrin loss-of-function mutations on eczema prevalence in children: A birth cohort study.
Toyokuni K, Yamamoto-Hanada K, Yang L, Hagino K, Harama D, Omori M, Matsumoto Y, Suzuki D, Umezawa K, Takada K, Shimada M, Hirai S, Ishikawa F, Hamaguchi S, Saito-Abe M, Sato M, Miyaji Y, Kabashima S, Fukuie T, Noguchi E, Suzuki K, Ohya Y. Toyokuni K, et al. Among authors: harama d. Allergol Int. 2024 Jan 31:S1323-8930(24)00004-2. doi: 10.1016/j.alit.2024.01.003. Online ahead of print. Allergol Int. 2024. PMID: 38302328 Free article.
Utility of ASNS gene methylation evaluated with the HPLC method as a pharmacogenomic biomarker to predict asparaginase sensitivity in BCP-ALL.
Watanabe A, Miyake K, Yamada Y, Sunamura EI, Yotani T, Kagami K, Kasai S, Tamai M, Harama D, Akahane K, Goi K, Sakaguchi K, Goto H, Kitahara S, Inukai T. Watanabe A, et al. Among authors: harama d. Epigenetics. 2023 Dec;18(1):2268814. doi: 10.1080/15592294.2023.2268814. Epub 2023 Oct 15. Epigenetics. 2023. PMID: 37839090 Free PMC article.
CRISPR/Cas9-Mediated Induction of Relapse-Specific NT5C2 and PRPS1 Mutations Confers Thiopurine Resistance as a Relapsed Lymphoid Leukemia Model.
Nguyen TTT, Tanaka Y, Sanada M, Hosaka M, Tamai M, Kagami K, Komatsu C, Somazu S, Harama D, Kasai S, Watanabe A, Akahane K, Goi K, Inukai T. Nguyen TTT, et al. Among authors: harama d. Mol Pharmacol. 2023 Apr;103(4):199-210. doi: 10.1124/molpharm.122.000546. Epub 2023 Jan 20. Mol Pharmacol. 2023. PMID: 36669880
Decreased incidence of acute immune thrombocytopenia in children during the COVID-19 pandemic.
Harama D, Goi K, Saito K, Sato H, Somazu S, Furuichi Y, Takahashi K, Oshiro H, Nakamura M, Sawanobori E, Sato K, Tsuruta M, Murakami Y, Shinohara T, Nemoto A, Kasai S, Tamai M, Watanabe A, Akahane K, Kojika S, Sugita K, Inukai T. Harama D, et al. Int J Hematol. 2023 Feb;117(2):307-308. doi: 10.1007/s12185-022-03521-7. Epub 2023 Jan 12. Int J Hematol. 2023. PMID: 36633776 Free PMC article. No abstract available.
Creation of Philadelphia chromosome by CRISPR/Cas9-mediated double cleavages on BCR and ABL1 genes as a model for initial event in leukemogenesis.
Tamai M, Fujisawa S, Nguyen TTT, Komatsu C, Kagami K, Kamimoto K, Omachi K, Kasai S, Harama D, Watanabe A, Akahane K, Goi K, Naka K, Kaname T, Teshima T, Inukai T. Tamai M, et al. Among authors: harama d. Cancer Gene Ther. 2023 Jan;30(1):38-50. doi: 10.1038/s41417-022-00522-w. Epub 2022 Aug 23. Cancer Gene Ther. 2023. PMID: 35999358 Free PMC article.
Successful treatment of intractable gastrointestinal tract graft-vs-host disease with oral beclomethasone dipropionate in pediatric and young adult patients: Case reports.
Akahane K, Watanabe A, Somazu S, Harama D, Shinohara T, Kasai S, Oshiro H, Goi K, Hasuda N, Ozawa C, Sugita K, Inukai T. Akahane K, et al. Among authors: harama d. Medicine (Baltimore). 2022 Mar 18;101(11):e29054. doi: 10.1097/MD.0000000000029054. Medicine (Baltimore). 2022. PMID: 35356922 Free PMC article.
NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells.
Somazu S, Tanaka Y, Tamai M, Watanabe A, Kagami K, Abe M, Harama D, Shinohara T, Akahane K, Goi K, Sugita K, Moriyama T, Yang J, Goto H, Minegishi M, Iwamoto S, Takita J, Inukai T. Somazu S, et al. Among authors: harama d. J Cell Mol Med. 2021 Nov;25(22):10521-10533. doi: 10.1111/jcmm.16981. Epub 2021 Oct 12. J Cell Mol Med. 2021. PMID: 34636169 Free PMC article.
Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL.
Akahane K, Kimura S, Miyake K, Watanabe A, Kagami K, Yoshimura K, Shinohara T, Harama D, Kasai S, Goi K, Kawai T, Hata K, Kiyokawa N, Koh K, Imamura T, Horibe K, Look AT, Minegishi M, Sugita K, Takita J, Inukai T. Akahane K, et al. Among authors: harama d. Blood Adv. 2022 Jan 11;6(1):212-224. doi: 10.1182/bloodadvances.2021004271. Blood Adv. 2022. PMID: 34535013 Free PMC article.
25 results