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SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion.
Cell. 2024 Feb 15;187(4):861-881.e32. doi: 10.1016/j.cell.2024.01.008. Epub 2024 Jan 31.
Cell. 2024.
PMID: 38301646
CRISPR-based genome editing through the lens of DNA repair.
Nambiar TS, Baudrier L, Billon P, Ciccia A.
Nambiar TS, et al.
Mol Cell. 2022 Jan 20;82(2):348-388. doi: 10.1016/j.molcel.2021.12.026.
Mol Cell. 2022.
PMID: 35063100
Free PMC article.
Review.
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MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.
Huang JW, Acharya A, Taglialatela A, Nambiar TS, Cuella-Martin R, Leuzzi G, Hayward SB, Joseph SA, Brunette GJ, Anand R, Soni RK, Clark NL, Bernstein KA, Cejka P, Ciccia A.
Huang JW, et al. Among authors: nambiar ts.
Nat Commun. 2020 Jun 11;11(1):2948. doi: 10.1038/s41467-020-16718-3.
Nat Commun. 2020.
PMID: 32528060
Free PMC article.
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Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures.
Billon P, Nambiar TS, Hayward SB, Zafra MP, Schatoff EM, Oshima K, Dunbar A, Breinig M, Park YC, Ryu HS, Tschaharganeh DF, Levine RL, Baer R, Ferrando A, Dow LE, Ciccia A.
Billon P, et al. Among authors: nambiar ts.
Cell Rep. 2020 Mar 10;30(10):3280-3295.e6. doi: 10.1016/j.celrep.2020.02.068.
Cell Rep. 2020.
PMID: 32160537
Free PMC article.
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Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant.
Nambiar TS, Billon P, Diedenhofen G, Hayward SB, Taglialatela A, Cai K, Huang JW, Leuzzi G, Cuella-Martin R, Palacios A, Gupta A, Egli D, Ciccia A.
Nambiar TS, et al.
Nat Commun. 2019 Jul 30;10(1):3395. doi: 10.1038/s41467-019-11105-z.
Nat Commun. 2019.
PMID: 31363085
Free PMC article.
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CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons.
Billon P, Bryant EE, Joseph SA, Nambiar TS, Hayward SB, Rothstein R, Ciccia A.
Billon P, et al. Among authors: nambiar ts.
Mol Cell. 2017 Sep 21;67(6):1068-1079.e4. doi: 10.1016/j.molcel.2017.08.008. Epub 2017 Sep 7.
Mol Cell. 2017.
PMID: 28890334
Free PMC article.
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