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A randomized first-in-human phase I trial of differentially adjuvanted Pfs48/45 malaria vaccines in Burkinabé adults.
Tiono AB, Plieskatt JL, Ouedraogo A, Soulama BI, Miura K, Bougouma EC, Naghizadeh M, Barry A, Yaro JBB, Ezinmegnon S, Henry N, Ofori EA, Adu B, Singh SK, Konkobo A, Lövgren Bengtsson K, Diarra A, Carnrot C, Reimer JM, Ouedraogo A, Tienta M, Long CA, Ouedraogo IN, Sagara I, Sirima SB, Theisen M. Tiono AB, et al. Among authors: plieskatt jl. J Clin Invest. 2024 Apr 1;134(7):e175707. doi: 10.1172/JCI175707. J Clin Invest. 2024. PMID: 38290009 Free PMC article. Clinical Trial.
A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial.
Alkema M, Smit MJ, Marin-Mogollon C, Totté K, Teelen K, van Gemert GJ, van de Vegte-Bolmer M, Mordmüller BG, Reimer JM, Lövgren-Bengtsson KL, Sauerwein RW, Bousema T, Plieskatt J, Theisen M, Jore MM, McCall MBB. Alkema M, et al. BMC Med. 2024 Apr 23;22(1):170. doi: 10.1186/s12916-024-03379-y. BMC Med. 2024. PMID: 38649867 Free PMC article. Clinical Trial.
A phase 1 study of the safety, reactogenicity, and immunogenicity of a Schistosoma mansoni vaccine with or without glucopyranosyl lipid A aqueous formulation (GLA-AF) in healthy adults from a non-endemic area.
Keitel WA, Potter GE, Diemert D, Bethony J, El Sahly HM, Kennedy JK, Patel SM, Plieskatt JL, Jones W, Deye G, Bottazzi ME, Hotez PJ, Atmar RL. Keitel WA, et al. Among authors: plieskatt jl. Vaccine. 2019 Oct 8;37(43):6500-6509. doi: 10.1016/j.vaccine.2019.08.075. Epub 2019 Sep 9. Vaccine. 2019. PMID: 31515141 Free PMC article. Clinical Trial.
ELISA units, IgG subclass ratio and avidity determined functional activity of mouse anti-Pfs230 antibodies judged by a standard membrane-feeding assay with Plasmodium falciparum.
Miura K, Deng B, Wu Y, Zhou L, Pham TP, Diouf A, Wu CK, Lee SM, Plieskatt JL, Morin MJ, Long CA. Miura K, et al. Among authors: plieskatt jl. Vaccine. 2019 Apr 3;37(15):2073-2078. doi: 10.1016/j.vaccine.2019.02.071. Epub 2019 Mar 5. Vaccine. 2019. PMID: 30850239 Free PMC article.
22 results