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Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Hossain MA, Sarin R, Donnelly DP, Miller BC, Weiss A, McAlary L, Antonyuk SV, Salisbury JP, Amin J, Conway JB, Watson SS, Winters JN, Xu Y, Alam N, Brahme RR, Shahbazian H, Sivasankar D, Padmakumar S, Sattarova A, Ponmudiyan AC, Gawde T, Verrill DE, Yang W, Kannapadi S, Plant LD, Auclair JR, Makowski L, Petsko GA, Ringe D, Agar NYR, Greenblatt DJ, Ondrechen MJ, Chen Y, Yerbury JJ, Manetsch R, Hasnain SS, Brown RH Jr, Agar JN. Hossain MA, et al. Among authors: plant ld. PLoS Biol. 2024 Jan 30;22(1):e3002462. doi: 10.1371/journal.pbio.3002462. eCollection 2024 Jan. PLoS Biol. 2024. PMID: 38289969 Free PMC article.
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.
Alexander SPH, Mathie AA, Peters JA, Veale EL, Striessnig J, Kelly E, Armstrong JF, Faccenda E, Harding SD, Davies JA, Aldrich RW, Attali B, Baggetta AM, Becirovic E, Biel M, Bill RM, Caceres AI, Catterall WA, Conner AC, Davies P, De Clerq K, Delling M, Di Virgilio F, Falzoni S, Fenske S, Fortuny-Gomez A, Fountain S, George C, Goldstein SAN, Grimm C, Grissmer S, Ha K, Hammelmann V, Hanukoglu I, Hu M, Ijzerman AP, Jabba SV, Jarvis M, Jensen AA, Jordt SE, Kaczmarek LK, Kellenberger S, Kennedy C, King B, Kitchen P, Liu Q, Lynch JW, Meades J, Mehlfeld V, Nicke A, Offermanns S, Perez-Reyes E, Plant LD, Rash L, Ren D, Salman MM, Sieghart W, Sivilotti LG, Smart TG, Snutch TP, Tian J, Trimmer JS, Van den Eynde C, Vriens J, Wei AD, Winn BT, Wulff H, Xu H, Yang F, Fang W, Yue L, Zhang X, Zhu M. Alexander SPH, et al. Among authors: plant ld. Br J Pharmacol. 2023 Oct;180 Suppl 2:S145-S222. doi: 10.1111/bph.16178. Br J Pharmacol. 2023. PMID: 38123150
PI(4,5)P2 regulates the gating of NaV1.4 channels.
Gada KD, Kamuene JM, Chandrashekar A, Kissell RC, Yauch AK, Plant LD. Gada KD, et al. Among authors: plant ld. J Gen Physiol. 2023 Jun 5;155(6):e202213255. doi: 10.1085/jgp.202213255. Epub 2023 Apr 12. J Gen Physiol. 2023. PMID: 37043561 Free PMC article.
Mechanism of PKCε regulation of cardiac GIRK channel gating.
Gada KD, Chang M, Chandrashekar A, Plant LD, Noujaim SF, Logothetis DE. Gada KD, et al. Among authors: plant ld. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2212325120. doi: 10.1073/pnas.2212325120. Epub 2022 Dec 30. Proc Natl Acad Sci U S A. 2023. PMID: 36584301 Free PMC article.
Preferential Gs protein coupling of the galanin Gal1 receptor in the µ-opioid-Gal1 receptor heterotetramer.
De Oliveira PA, Moreno E, Casajuana-Martin N, Casadó-Anguera V, Cai NS, Camacho-Hernandez GA, Zhu H, Bonifazi A, Hall MD, Weinshenker D, Newman AH, Logothetis DE, Casadó V, Plant LD, Pardo L, Ferré S. De Oliveira PA, et al. Among authors: plant ld. Pharmacol Res. 2022 Aug;182:106322. doi: 10.1016/j.phrs.2022.106322. Epub 2022 Jun 22. Pharmacol Res. 2022. PMID: 35750299 Free PMC article.
A novel small-molecule selective activator of homomeric GIRK4 channels.
Cui M, Xu K, Gada KD, Shalomov B, Ban M, Eptaminitaki GC, Kawano T, Plant LD, Dascal N, Logothetis DE. Cui M, et al. Among authors: plant ld. J Biol Chem. 2022 Jun;298(6):102009. doi: 10.1016/j.jbc.2022.102009. Epub 2022 May 4. J Biol Chem. 2022. PMID: 35525275 Free PMC article.
57 results