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A bacteria-based genetic assay detects prion formation.
Fleming E, Yuan AH, Heller DM, Hochschild A. Fleming E, et al. Among authors: hochschild a. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4605-4610. doi: 10.1073/pnas.1817711116. Epub 2019 Feb 19. Proc Natl Acad Sci U S A. 2019. PMID: 30782808 Free PMC article.
Measuring prion propagation in single bacteria elucidates a mechanism of loss.
Jager K, Orozco-Hidalgo MT, Springstein BL, Joly-Smith E, Papazotos F, McDonough E, Fleming E, McCallum G, Yuan AH, Hilfinger A, Hochschild A, Potvin-Trottier L. Jager K, et al. Among authors: hochschild a. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2221539120. doi: 10.1073/pnas.2221539120. Epub 2023 Sep 22. Proc Natl Acad Sci U S A. 2023. PMID: 37738299 Free PMC article.
Conversion of a yeast prion protein to an infectious form in bacteria.
Garrity SJ, Sivanathan V, Dong J, Lindquist S, Hochschild A. Garrity SJ, et al. Among authors: hochschild a. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10596-601. doi: 10.1073/pnas.0913280107. Epub 2010 May 19. Proc Natl Acad Sci U S A. 2010. PMID: 20484678 Free PMC article.
Bacterial RNA polymerase can retain σ70 throughout transcription.
Harden TT, Wells CD, Friedman LJ, Landick R, Hochschild A, Kondev J, Gelles J. Harden TT, et al. Among authors: hochschild a. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):602-7. doi: 10.1073/pnas.1513899113. Epub 2016 Jan 5. Proc Natl Acad Sci U S A. 2016. PMID: 26733675 Free PMC article.
Isolation of peptide aptamers that inhibit intracellular processes.
Blum JH, Dove SL, Hochschild A, Mekalanos JJ. Blum JH, et al. Among authors: hochschild a. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2241-6. doi: 10.1073/pnas.040573397. Proc Natl Acad Sci U S A. 2000. PMID: 10688899 Free PMC article.
99 results