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Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies.
Farouk F, Elmaaty AA, Elkamhawy A, Tawfik HO, Alnajjar R, Abourehab MAS, Saleh MA, Eldehna WM, Al-Karmalawy AA. Farouk F, et al. Among authors: tawfik ho. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2171029. doi: 10.1080/14756366.2023.2171029. J Enzyme Inhib Med Chem. 2023. PMID: 36701269 Free PMC article.
2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling.
Shaldam MA, Hendrychová D, El-Haggar R, Vojáčková V, Majrashi TA, Elkaeed EB, Masurier N, Kryštof V, Tawfik HO, Eldehna WM. Shaldam MA, et al. Among authors: tawfik ho. Eur J Med Chem. 2023 Oct 5;258:115610. doi: 10.1016/j.ejmech.2023.115610. Epub 2023 Jun 27. Eur J Med Chem. 2023. PMID: 37437350
Novel 4-(2-arylidenehydrazineyl)thienopyrimidine derivatives as anticancer EGFR inhibitors: Design, synthesis, biological evaluation, kinome selectivity and in silico insights.
Elsebaie HA, El-Bastawissy EA, Elberembally KM, Khaleel EF, Badi RM, Shaldam MA, Eldehna WM, Tawfik HO, El-Moselhy TF. Elsebaie HA, et al. Among authors: tawfik ho. Bioorg Chem. 2023 Nov;140:106799. doi: 10.1016/j.bioorg.2023.106799. Epub 2023 Aug 22. Bioorg Chem. 2023. PMID: 37625210
35 results