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The ACE inhibitor captopril inhibits ACN-1 to control dauer formation and aging.
Egan BM, Pohl F, Anderson X, Williams SC, Gregory Adodo I, Hunt P, Wang Z, Chiu CH, Scharf A, Mosley M, Kumar S, Schneider DL, Fujiwara H, Hsu FF, Kornfeld K. Egan BM, et al. Among authors: wang z. Development. 2024 Feb 1;151(3):dev202146. doi: 10.1242/dev.202146. Epub 2024 Feb 12. Development. 2024. PMID: 38284547
The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and aging.
Egan BM, Pohl F, Anderson X, Williams SC, Adodo IG, Hunt P, Wang Z, Chiu CH, Scharf A, Mosley M, Kumar S, Schneider DL, Fujiwara H, Hsu FF, Kornfeld K. Egan BM, et al. Among authors: wang z. bioRxiv [Preprint]. 2023 Jul 19:2023.07.17.549402. doi: 10.1101/2023.07.17.549402. bioRxiv. 2023. PMID: 37502959 Free PMC article. Updated. Preprint.
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model.
Hou J, Chen Y, Cai Z, Heo GS, Yuede CM, Wang Z, Lin K, Saadi F, Trsan T, Nguyen AT, Constantopoulos E, Larsen RA, Zhu Y, Wagner ND, McLaughlin N, Kuang XC, Barrow AD, Li D, Zhou Y, Wang S, Gilfillan S, Gross ML, Brioschi S, Liu Y, Holtzman DM, Colonna M. Hou J, et al. Among authors: wang z, wang s. Sci Transl Med. 2024 Apr 3;16(741):eadj9052. doi: 10.1126/scitranslmed.adj9052. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569016
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