Wang X - Search Results

1

Annual review of PROTAC degraders as anticancer agents in 2022.

Wang X, Qin ZL, Li N, Jia MQ, Liu QG, Bai YR, Song J, Yuan S, Zhang SY. Wang X, et al. Eur J Med Chem. 2024 Mar 5;267:116166. doi: 10.1016/j.ejmech.2024.116166. Epub 2024 Jan 25. Eur J Med Chem. 2024. PMID: 38281455 Review.

2

Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer.

Yuan K, Shen H, Zheng M, Xia F, Li Q, Chen W, Ji M, Yang H, Zhuang X, Cai Z, Min W, Wang X, Xiao Y, Yang P. Yuan K, et al. Among authors: wang x. J Med Chem. 2023 Mar 23;66(6):4215-4230. doi: 10.1021/acs.jmedchem.3c00106. Epub 2023 Feb 17. J Med Chem. 2023. PMID: 36800260

3

Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation.

Zhu Y, Ye X, Wu Y, Shen H, Cai Z, Xia F, Min W, Hou Y, Wang L, Wang X, Xiao Y, Yang P. Zhu Y, et al. Among authors: wang x, wang l. J Med Chem. 2024 May 9;67(9):7283-7300. doi: 10.1021/acs.jmedchem.4c00107. Epub 2024 Apr 27. J Med Chem. 2024. PMID: 38676656

4

Pyrazolone structural motif in medicinal chemistry: Retrospect and prospect.

Zhao Z, Dai X, Li C, Wang X, Tian J, Feng Y, Xie J, Ma C, Nie Z, Fan P, Qian M, He X, Wu S, Zhang Y, Zheng X. Zhao Z, et al. Among authors: wang x. Eur J Med Chem. 2020 Jan 15;186:111893. doi: 10.1016/j.ejmech.2019.111893. Epub 2019 Nov 16. Eur J Med Chem. 2020. PMID: 31761383 Free PMC article. Review.

5

Novel Small-Molecule PD-L1 Inhibitor Induces PD-L1 Internalization and Optimizes the Immune Microenvironment.

Sun C, Yin M, Cheng Y, Kuang Z, Liu X, Wang G, Wang X, Yuan K, Min W, Dong J, Hou Y, Hu L, Zhang G, Pei W, Wang L, Sun Y, Yu X, Xiao Y, Deng H, Yang P. Sun C, et al. Among authors: wang x, wang g, wang l. J Med Chem. 2023 Feb 9;66(3):2064-2083. doi: 10.1021/acs.jmedchem.2c01801. Epub 2022 Dec 29. J Med Chem. 2023. PMID: 36579489

6

Discovery of Novel Fourth-Generation EGFR Inhibitors to Overcome C797S-Mediated Resistance.

Zhu Y, Ye X, Shen H, Li J, Cai Z, Min W, Hou Y, Dong H, Wu Y, Wang L, Wang X, Xiao Y, Yang P. Zhu Y, et al. Among authors: wang x, wang l. J Med Chem. 2023 Nov 9;66(21):14633-14652. doi: 10.1021/acs.jmedchem.3c01165. Epub 2023 Oct 27. J Med Chem. 2023. PMID: 37885208

7

Discovery of potent and selective c-Met inhibitors for MET-amplified hepatocellular carcinoma treatment.

Min W, Wang Y, Shen H, Zheng M, Tong C, Shen H, Wang D, Zhu Y, Wang X, Xiao Y, Zhang XY, Yang P. Min W, et al. Among authors: wang x, wang y, wang d. Eur J Med Chem. 2024 Jan 15;264:116025. doi: 10.1016/j.ejmech.2023.116025. Epub 2023 Dec 5. Eur J Med Chem. 2024. PMID: 38086189

8

Design, Synthesis, and Antitumor Activity Evaluation of Novel VISTA Small Molecule Inhibitors.

Sun C, He Y, Wang G, Zhang G, Zhang Y, Shen H, Hu L, Sun Y, Jiang B, Wang X, Yuan K, Min W, Wang L, Sun H, Xiao Y, Yang P. Sun C, et al. Among authors: wang x, wang g, wang l. J Med Chem. 2024 Mar 14;67(5):3590-3605. doi: 10.1021/acs.jmedchem.3c02039. Epub 2024 Feb 27. J Med Chem. 2024. PMID: 38412237

9

Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents.

Sun C, Cheng Y, Liu X, Wang G, Min W, Wang X, Yuan K, Hou Y, Li J, Zhang H, Dong H, Wang L, Lou C, Sun Y, Yu X, Deng H, Xiao Y, Yang P. Sun C, et al. Among authors: wang x, wang g, wang l. Acta Pharm Sin B. 2022 Dec;12(12):4446-4457. doi: 10.1016/j.apsb.2022.04.007. Epub 2022 Apr 16. Acta Pharm Sin B. 2022. PMID: 36561991 Free PMC article.

10

Bispecific antibodies in cancer therapy: Target selection and regulatory requirements.

Sun Y, Yu X, Wang X, Yuan K, Wang G, Hu L, Zhang G, Pei W, Wang L, Sun C, Yang P. Sun Y, et al. Among authors: wang x, wang g, wang l. Acta Pharm Sin B. 2023 Sep;13(9):3583-3597. doi: 10.1016/j.apsb.2023.05.023. Epub 2023 May 23. Acta Pharm Sin B. 2023. PMID: 37719370 Free PMC article. Review.

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