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Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset.
Xu Y, Nipper MH, Dominguez AA, Ye Z, Akanuma N, Lopez K, Deng JJ, Arenas D, Sanchez A, Sharkey FE, Court CM, Singhi AD, Wang H, Fernandez-Zapico ME, Sun LZ, Zheng S, Chen Y, Liu J, Wang P. Xu Y, et al. Among authors: fernandez zapico me. Nat Commun. 2024 Jan 27;15(1):818. doi: 10.1038/s41467-024-45097-2. Nat Commun. 2024. PMID: 38280869 Free PMC article.
IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis.
Rajurkar M, Dang K, Fernandez-Barrena MG, Liu X, Fernandez-Zapico ME, Lewis BC, Mao J. Rajurkar M, et al. Cancer Res. 2017 Jan 15;77(2):320-329. doi: 10.1158/0008-5472.CAN-15-1684. Epub 2017 Jan 9. Cancer Res. 2017. PMID: 28069799 Free PMC article.
Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas.
Lenkiewicz E, Malasi S, Hogenson TL, Flores LF, Barham W, Phillips WJ, Roesler AS, Chambers KR, Rajbhandari N, Hayashi A, Antal CE, Downes M, Grandgenett PM, Hollingsworth MA, Cridebring D, Xiong Y, Lee JH, Ye Z, Yan H, Hernandez MC, Leiting JL, Evans RM, Ordog T, Truty MJ, Borad MJ, Reya T, Von Hoff DD, Fernandez-Zapico ME, Barrett MT. Lenkiewicz E, et al. Cancer Res. 2020 Oct 15;80(20):4324-4334. doi: 10.1158/0008-5472.CAN-20-0078. Epub 2020 Sep 14. Cancer Res. 2020. PMID: 32928922 Free PMC article.
RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis.
Carr RM, Vorobyev D, Lasho T, Marks DL, Tolosa EJ, Vedder A, Almada LL, Yurcheko A, Padioleau I, Alver B, Coltro G, Binder M, Safgren SL, Horn I, You X, Solary E, Balasis ME, Berger K, Hiebert J, Witzig T, Buradkar A, Graf T, Valent P, Mangaonkar AA, Robertson KD, Howard MT, Kaufmann SH, Pin C, Fernandez-Zapico ME, Geissler K, Droin N, Padron E, Zhang J, Nikolaev S, Patnaik MM. Carr RM, et al. Nat Commun. 2021 May 18;12(1):2901. doi: 10.1038/s41467-021-23186-w. Nat Commun. 2021. PMID: 34006870 Free PMC article.
Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion.
Gutierrez-Ruiz OL, Johnson KM, Krueger EW, Nooren RE, Cruz-Reyes N, Heppelmann CJ, Hogenson TL, Fernandez-Zapico ME, McNiven MA, Razidlo GL. Gutierrez-Ruiz OL, et al. Among authors: fernandez zapico me. Cell Rep. 2023 Sep 26;42(9):113042. doi: 10.1016/j.celrep.2023.113042. Epub 2023 Aug 30. Cell Rep. 2023. PMID: 37651233 Free PMC article.
174 results