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The Amino-Terminal Oligomerization Domain of Angiopoietin-2 Affects Vascular Remodeling, Mammary Gland Tumor Growth, and Lung Metastasis in Mice.
Kapiainen E, Kihlström MK, Pietilä R, Kaakinen M, Ronkainen VP, Tu H, Heikkinen A, Devarajan R, Miinalainen I, Laitakari A, Ansarizadeh M, Zhang Q, Wei GH, Ruddock L, Pihlajaniemi T, Elamaa H, Eklund L. Kapiainen E, et al. Among authors: kaakinen m. Cancer Res. 2021 Jan 1;81(1):129-143. doi: 10.1158/0008-5472.CAN-19-1904. Epub 2020 Oct 9. Cancer Res. 2021. PMID: 33037065
Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention.
Åkerfelt M, Bayramoglu N, Robinson S, Toriseva M, Schukov HP, Härmä V, Virtanen J, Sormunen R, Kaakinen M, Kannala J, Eklund L, Heikkilä J, Nees M. Åkerfelt M, et al. Among authors: kaakinen m. Oncotarget. 2015 Oct 6;6(30):30035-56. doi: 10.18632/oncotarget.5046. Oncotarget. 2015. PMID: 26375443 Free PMC article.
Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis.
Jin Y, Ding Y, Richards M, Kaakinen M, Giese W, Baumann E, Szymborska A, Rosa A, Nordling S, Schimmel L, Akmeriç EB, Pena A, Nwadozi E, Jamalpour M, Holstein K, Sáinz-Jaspeado M, Bernabeu MO, Welsh M, Gordon E, Franco CA, Vestweber D, Eklund L, Gerhardt H, Claesson-Welsh L. Jin Y, et al. Among authors: kaakinen m. Nat Cardiovasc Res. 2022 Dec 7;1(12):1156-1173. doi: 10.1038/s44161-022-00172-z. Nat Cardiovasc Res. 2022. PMID: 37936984 Free PMC article.
189 results