Pang J - Search Results

1

A New Approach for Preparing Stable High-Concentration Peptide Nanoparticle Formulations.

Hu C, Zang N, Tam YT, Dizon D, Lee K, Pang J, Torres E, Cui Y, Yen CW, Leung DH. Hu C, et al. Among authors: pang j. Pharmaceuticals (Basel). 2023 Dec 21;17(1):15. doi: 10.3390/ph17010015. Pharmaceuticals (Basel). 2023. PMID: 38276000 Free PMC article.

2

Early Stage Preclinical Formulation Strategies to Alter the Pharmacokinetic Profile of Two Small Molecule Therapeutics.

An L, De Bruyn T, Pang J, Ubhayakar S, Salphati L, Zhang X, Liu L, Li R, Chan B, Dey A, Levy ES. An L, et al. Among authors: pang j. Pharmaceuticals (Basel). 2024 Jan 30;17(2):179. doi: 10.3390/ph17020179. Pharmaceuticals (Basel). 2024. PMID: 38399394 Free PMC article.

3

An Investigation of Oral Exposure Variability and Formulation Strategy: A Case Study of PI3Kδ Inhibitor and Physiologically Based Pharmacokinetic Modeling in Beagle Dogs.

Chiang PC, Pang J, Liu J, Salphati L. Chiang PC, et al. Among authors: pang j. J Pharm Sci. 2018 Jan;107(1):466-475. doi: 10.1016/j.xphs.2017.06.014. Epub 2017 Jun 23. J Pharm Sci. 2018. PMID: 28652157

4

Investigation of Dose-Dependent Factors Limiting Oral Bioavailability: Case Study With the PI3K-δ Inhibitor.

Chiang PC, Sutherlin D, Pang J, Salphati L. Chiang PC, et al. Among authors: pang j. J Pharm Sci. 2016 Jun;105(6):1802-1809. doi: 10.1016/j.xphs.2016.04.003. J Pharm Sci. 2016. PMID: 27238480

5

Unequal Absorption of Radiolabeled and Nonradiolabeled Drug from the Oral Dose Leads to Incorrect Estimates of Drug Absorption and Circulating Metabolites in a Mass Balance Study.

Takahashi RH, Chang JH, Pang J, Liang X, Ma S. Takahashi RH, et al. Among authors: pang j. Drug Metab Lett. 2019;13(1):37-44. doi: 10.2174/1872312813666181129162237. Drug Metab Lett. 2019. PMID: 30499424

6

Preclinical characterization of the absorption and disposition of the brain penetrant PI3K/mTOR inhibitor paxalisib and prediction of its pharmacokinetics and efficacy in human.

Salphati L, Pang J, Alicke B, Plise EG, Cheong J, Jaochico A, Olivero AG, Sampath D, Wong S, Zhang X. Salphati L, et al. Among authors: pang j. Xenobiotica. 2024 Feb;54(2):64-74. doi: 10.1080/00498254.2024.2303586. Epub 2024 Jan 15. Xenobiotica. 2024. PMID: 38197324

7

Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) kinase inhibitor (GDC-0980) for the treatment of cancer.

Sutherlin DP, Bao L, Berry M, Castanedo G, Chuckowree I, Dotson J, Folks A, Friedman L, Goldsmith R, Gunzner J, Heffron T, Lesnick J, Lewis C, Mathieu S, Murray J, Nonomiya J, Pang J, Pegg N, Prior WW, Rouge L, Salphati L, Sampath D, Tian Q, Tsui V, Wan NC, Wang S, Wei B, Wiesmann C, Wu P, Zhu BY, Olivero A. Sutherlin DP, et al. Among authors: pang j. J Med Chem. 2011 Nov 10;54(21):7579-87. doi: 10.1021/jm2009327. Epub 2011 Oct 7. J Med Chem. 2011. PMID: 21981714

8

Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation.

Dorel R, Sun D, Carruthers N, Castanedo GM, Ung PM, Factor DC, Li T, Baumann H, Janota D, Pang J, Salphati L, Meklemburg R, Korman AJ, Harper HE, Stubblefield S, Payandeh J, McHugh D, Lang BT, Tesar PJ, Dere E, Masureel M, Adams DJ, Volgraf M, Braun MG. Dorel R, et al. Among authors: pang j. J Med Chem. 2024 Mar 28;67(6):4819-4832. doi: 10.1021/acs.jmedchem.3c02396. Epub 2024 Mar 12. J Med Chem. 2024. PMID: 38470227

9

Absorption, Metabolism, and Excretion of Taselisib (GDC-0032), a Potent β-Sparing PI3K Inhibitor in Rats, Dogs, and Humans.

Ma S, Cho S, Sahasranaman S, Zhao W, Pang J, Ding X, Dean B, Wang B, Hsu JY, Ware J, Salphati L. Ma S, et al. Among authors: pang j. Drug Metab Dispos. 2023 Apr;51(4):436-450. doi: 10.1124/dmd.122.001096. Epub 2023 Jan 9. Drug Metab Dispos. 2023. PMID: 36623882

10

Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na_V) 1.7 with Potent Analgesic Activity.

Sun S, Jia Q, Zenova AY, Wilson MS, Chowdhury S, Focken T, Li J, Decker S, Grimwood ME, Andrez JC, Hemeon I, Sheng T, Chen CA, White A, Hackos DH, Deng L, Bankar G, Khakh K, Chang E, Kwan R, Lin S, Nelkenbrecher K, Sellers BD, DiPasquale AG, Chang J, Pang J, Sojo L, Lindgren A, Waldbrook M, Xie Z, Young C, Johnson JP, Robinette CL, Cohen CJ, Safina BS, Sutherlin DP, Ortwine DF, Dehnhardt CM. Sun S, et al. Among authors: pang j. J Med Chem. 2019 Jan 24;62(2):908-927. doi: 10.1021/acs.jmedchem.8b01621. Epub 2018 Dec 21. J Med Chem. 2019. PMID: 30499663

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

3,775 results

Search Page