Zhang Q - Search Results

1

Tracing the substrate translocation mechanism in P-glycoprotein.

Gewering T, Waghray D, Parey K, Jung H, Tran NNB, Zapata J, Zhao P, Chen H, Januliene D, Hummer G, Urbatsch I, Moeller A, Zhang Q. Gewering T, et al. Among authors: zhang q. Elife. 2024 Jan 23;12:RP90174. doi: 10.7554/eLife.90174. Elife. 2024. PMID: 38259172 Free PMC article.

2

Inhibit or Evade Multidrug Resistance P-Glycoprotein in Cancer Treatment.

Waghray D, Zhang Q. Waghray D, et al. Among authors: zhang q. J Med Chem. 2018 Jun 28;61(12):5108-5121. doi: 10.1021/acs.jmedchem.7b01457. Epub 2017 Dec 28. J Med Chem. 2018. PMID: 29251920 Free PMC article. Review.

3

Lipid environment determines the drug-stimulated ATPase activity of P-glycoprotein.

Tran NNB, Bui ATA, Jaramillo-Martinez V, Weber J, Zhang Q, Urbatsch IL. Tran NNB, et al. Among authors: zhang q. Front Mol Biosci. 2023 Feb 23;10:1141081. doi: 10.3389/fmolb.2023.1141081. eCollection 2023. Front Mol Biosci. 2023. PMID: 36911528 Free PMC article.

4

Distinct conformational spectrum of homologous multidrug ABC transporters.

Moeller A, Lee SC, Tao H, Speir JA, Chang G, Urbatsch IL, Potter CS, Carragher B, Zhang Q. Moeller A, et al. Among authors: zhang q. Structure. 2015 Mar 3;23(3):450-460. doi: 10.1016/j.str.2014.12.013. Epub 2015 Feb 5. Structure. 2015. PMID: 25661651 Free PMC article.

5

Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.

Szewczyk P, Tao H, McGrath AP, Villaluz M, Rees SD, Lee SC, Doshi R, Urbatsch IL, Zhang Q, Chang G. Szewczyk P, et al. Among authors: zhang q. Acta Crystallogr D Biol Crystallogr. 2015 Mar;71(Pt 3):732-41. doi: 10.1107/S1399004715000978. Epub 2015 Feb 26. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 25760620 Free PMC article.

6

Design and synthesis of Selenazole-containing peptides for cocrystallization with P-glycoprotein.

Tao H, Weng Y, Zhuo R, Chang G, Urbatsch IL, Zhang Q. Tao H, et al. Among authors: zhang q. Chembiochem. 2011 Apr 11;12(6):868-73. doi: 10.1002/cbic.201100048. Epub 2011 Mar 8. Chembiochem. 2011. PMID: 21387512 Free PMC article. No abstract available.

7

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.

Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Zhang Q, Urbatsch IL, Chang G. Aller SG, et al. Among authors: zhang q. Science. 2009 Mar 27;323(5922):1718-22. doi: 10.1126/science.1168750. Science. 2009. PMID: 19325113 Free PMC article.

8

Engineered nanostructured β-sheet peptides protect membrane proteins.

Tao H, Lee SC, Moeller A, Roy RS, Siu FY, Zimmermann J, Stevens RC, Potter CS, Carragher B, Zhang Q. Tao H, et al. Among authors: zhang q. Nat Methods. 2013 Aug;10(8):759-61. doi: 10.1038/nmeth.2533. Epub 2013 Jun 30. Nat Methods. 2013. PMID: 23817067 Free PMC article.

9

A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR).

Hildebrandt E, Zhang Q, Cant N, Ding H, Dai Q, Peng L, Fu Y, DeLucas LJ, Ford R, Kappes JC, Urbatsch IL. Hildebrandt E, et al. Among authors: zhang q. Biochim Biophys Acta. 2014 Nov;1838(11):2825-37. doi: 10.1016/j.bbamem.2014.07.016. Epub 2014 Jul 24. Biochim Biophys Acta. 2014. PMID: 25065669 Free PMC article.

10

Contributions of ionic interactions and protein dynamics to cytochrome P450 2D6 (CYP2D6) substrate and inhibitor binding.

Wang A, Stout CD, Zhang Q, Johnson EF. Wang A, et al. Among authors: zhang q. J Biol Chem. 2015 Feb 20;290(8):5092-5104. doi: 10.1074/jbc.M114.627661. Epub 2015 Jan 1. J Biol Chem. 2015. PMID: 25555909 Free PMC article.

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