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KCNQ1 p.D446E Variant as a Risk Allele for Arrhythmogenic Phenotypes: Electrophysiological Characterization Reveals a Complex Phenotype Affecting the Slow Delayed Rectifier Potassium Current (IKs) Voltage Dependence by Causing a Hyperpolarizing Shift and a Lack of Response to Protein Kinase A Activation.
Int J Mol Sci. 2024 Jan 12;25(2):953. doi: 10.3390/ijms25020953.
Int J Mol Sci. 2024.
PMID: 38256028
Free PMC article.
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