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MediMer: a versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection.
Meyer M, Parpoulas C, Barthélémy T, Becker JP, Charoentong P, Lyu Y, Börsig S, Bulbuc N, Tessmer C, Weinacht L, Ibberson D, Schmidt P, Pipkorn R, Eichmüller SB, Steinberger P, Lindner K, Poschke I, Platten M, Fröhling S, Riemer AB, Hassel JC, Roberti MP, Jäger D, Zörnig I, Momburg F. Meyer M, et al. Among authors: charoentong p. Front Immunol. 2024 Jan 4;14:1294565. doi: 10.3389/fimmu.2023.1294565. eCollection 2023. Front Immunol. 2024. PMID: 38239352 Free PMC article.
Graph machine learning for integrated multi-omics analysis.
Valous NA, Popp F, Zörnig I, Jäger D, Charoentong P. Valous NA, et al. Among authors: charoentong p. Br J Cancer. 2024 May 10. doi: 10.1038/s41416-024-02706-7. Online ahead of print. Br J Cancer. 2024. PMID: 38729996 Review.
Democratizing knowledge representation with BioCypher.
Lobentanzer S, Aloy P, Baumbach J, Bohar B, Carey VJ, Charoentong P, Danhauser K, Doğan T, Dreo J, Dunham I, Farr E, Fernandez-Torras A, Gyori BM, Hartung M, Hoyt CT, Klein C, Korcsmaros T, Maier A, Mann M, Ochoa D, Pareja-Lorente E, Popp F, Preusse M, Probul N, Schwikowski B, Sen B, Strauss MT, Turei D, Ulusoy E, Waltemath D, Wodke JAH, Saez-Rodriguez J. Lobentanzer S, et al. Among authors: charoentong p. Nat Biotechnol. 2023 Aug;41(8):1056-1059. doi: 10.1038/s41587-023-01848-y. Nat Biotechnol. 2023. PMID: 37337100 No abstract available.
Tumor-specific T cells support chemokine-driven spatial organization of intratumoral immune microaggregates needed for long survival.
Abdulrahman Z, Santegoets SJ, Sturm G, Charoentong P, Ijsselsteijn ME, Somarakis A, Höllt T, Finotello F, Trajanoski Z, van Egmond SL, Mustafa DAM, Welters MJP, de Miranda NFCC, van der Burg SH. Abdulrahman Z, et al. Among authors: charoentong p. J Immunother Cancer. 2022 Feb;10(2):e004346. doi: 10.1136/jitc-2021-004346. J Immunother Cancer. 2022. PMID: 35217577 Free PMC article.
NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division.
Borst L, Sluijter M, Sturm G, Charoentong P, Santegoets SJ, van Gulijk M, van Elsas MJ, Groeneveldt C, van Montfoort N, Finotello F, Trajanoski Z, Kiełbasa SM, van der Burg SH, van Hall T. Borst L, et al. Among authors: charoentong p. Int J Cancer. 2022 Feb 15;150(4):688-704. doi: 10.1002/ijc.33859. Epub 2021 Nov 10. Int J Cancer. 2022. PMID: 34716584 Free PMC article.
Primary vulvar squamous cell carcinomas with high T cell infiltration and active immune signaling are potential candidates for neoadjuvant PD-1/PD-L1 immunotherapy.
Kortekaas KE, Santegoets SJ, Tas L, Ehsan I, Charoentong P, van Doorn HC, van Poelgeest MIE, Mustafa DAM, van der Burg SH. Kortekaas KE, et al. Among authors: charoentong p. J Immunother Cancer. 2021 Oct;9(10):e003671. doi: 10.1136/jitc-2021-003671. J Immunother Cancer. 2021. PMID: 34716208 Free PMC article.
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction.
Wells DK, van Buuren MM, Dang KK, Hubbard-Lucey VM, Sheehan KCF, Campbell KM, Lamb A, Ward JP, Sidney J, Blazquez AB, Rech AJ, Zaretsky JM, Comin-Anduix B, Ng AHC, Chour W, Yu TV, Rizvi H, Chen JM, Manning P, Steiner GM, Doan XC; Tumor Neoantigen Selection Alliance; Merghoub T, Guinney J, Kolom A, Selinsky C, Ribas A, Hellmann MD, Hacohen N, Sette A, Heath JR, Bhardwaj N, Ramsdell F, Schreiber RD, Schumacher TN, Kvistborg P, Defranoux NA. Wells DK, et al. Cell. 2020 Oct 29;183(3):818-834.e13. doi: 10.1016/j.cell.2020.09.015. Epub 2020 Oct 9. Cell. 2020. PMID: 33038342 Free PMC article.
Frequent Molecular Subtype Switching and Gene Expression Alterations in Lung and Pleural Metastasis From Luminal A-Type Breast Cancer.
Klebe M, Fremd C, Kriegsmann M, Kriegsmann K, Albrecht T, Thewes V, Kirchner M, Charoentong P, Volk N, Haag J, Wirtz R, Oskarsson T, Schulz A, Heil J, Schneeweiss A, Winter H, Sinn P. Klebe M, et al. Among authors: charoentong p. JCO Precis Oncol. 2020 Jul 24;4:PO.19.00337. doi: 10.1200/PO.19.00337. eCollection 2020. JCO Precis Oncol. 2020. PMID: 32923902 Free PMC article.
IDO1+ Paneth cells promote immune escape of colorectal cancer.
Pflügler S, Svinka J, Scharf I, Crncec I, Filipits M, Charoentong P, Tschurtschenthaler M, Kenner L, Awad M, Stift J, Schernthanner M, Bischl R, Herndler-Brandstetter D, Glitzner E, Moll HP, Casanova E, Timelthaler G, Sibilia M, Gnant M, Lax S, Thaler J, Müller M, Strobl B, Mohr T, Kaser A, Trajanoski Z, Heller G, Eferl R. Pflügler S, et al. Among authors: charoentong p. Commun Biol. 2020 May 22;3(1):252. doi: 10.1038/s42003-020-0989-y. Commun Biol. 2020. PMID: 32444775 Free PMC article.
38 results