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Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity.
Lin QXX, Rajagopalan D, Gamage AM, Tan LM, Venkatesh PN, Chan WOY, Kumar D, Agrawal R, Chen Y, Fong SW, Singh A, Sun LJ, Tan SY, Chai LYA, Somani J, Lee B, Renia L, Ng LFP, Ramanathan K, Wang LF, Young B, Lye D, Singhal A, Prabhakar S. Lin QXX, et al. Among authors: chan woy. Nat Commun. 2024 Jan 18;15(1):567. doi: 10.1038/s41467-023-44524-0. Nat Commun. 2024. PMID: 38238298 Free PMC article.
Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles.
Gamage AM, Tan KS, Chan WOY, Liu J, Tan CW, Ong YK, Thong M, Andiappan AK, Anderson DE, Wang Y, Wang LF. Gamage AM, et al. Among authors: chan woy. PLoS Pathog. 2020 Dec 7;16(12):e1009130. doi: 10.1371/journal.ppat.1009130. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33284849 Free PMC article.
Betacoronaviruses SARS-CoV-2 and HCoV-OC43 infections in IGROV-1 cell line require aryl hydrocarbon receptor.
Yousefi M, Lee WS, Chan WOY, He W, Mah MG, Yong CL, Deerain JM, Wang L, Arcinas C, Yan B, Tan D, Sia WR, Gamage AM, Yang J, Hsu AC, Li S, Linster M, Yang X, Ghosh S, Anderson DE, Smith GJD, Tan CW, Wang LF, Ooi YS. Yousefi M, et al. Among authors: chan woy. Emerg Microbes Infect. 2023 Dec;12(2):2256416. doi: 10.1080/22221751.2023.2256416. Epub 2023 Sep 6. Emerg Microbes Infect. 2023. PMID: 37672505 Free PMC article.
Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases.
Ahn M, Chen VC, Rozario P, Ng WL, Kong PS, Sia WR, Kang AEZ, Su Q, Nguyen LH, Zhu F, Chan WOY, Tan CW, Cheong WS, Hey YY, Foo R, Guo F, Lim YT, Li X, Chia WN, Sobota RM, Fu NY, Irving AT, Wang LF. Ahn M, et al. Among authors: chan woy. Cell. 2023 May 11;186(10):2144-2159.e22. doi: 10.1016/j.cell.2023.03.036. Cell. 2023. PMID: 37172565