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Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders.
Diemar MG, Vinken M, Teunis M, Krul CAM, Busquet F, Zajac JD, Kandarova H, Corvi R, Rosso MZ, Kharina A, Bryndum LS, Santillo M, Bloch D, Kucheryavenko O, Panagiotakos D, Rogiers V, Beekhuijzen M, Giusti A, Najjar A, Courage C, Koenig T, Kolle S, Boonen H, Dhalluin S, Boberg J, Müller BP, Kukic P, Ritskes-Hoitinga M, Grasselli E, Zietek T, Stoddart G, Heusinkveld HJ, Castell JV, Benfenati E, Yang H, Perera S, Paini A, Kramer NI, Hartung T, Janssen M, Fritsche E, Jennen DGJ, Piumatti M, Rathman J, Marusczyk J, Milec L, Roggen EL. Diemar MG, et al. Among authors: najjar a. Altern Lab Anim. 2024 Mar;52(2):117-131. doi: 10.1177/02611929231225730. Epub 2024 Jan 18. Altern Lab Anim. 2024. PMID: 38235727 Free article.
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment.
Najjar A, Punt A, Wambaugh J, Paini A, Ellison C, Fragki S, Bianchi E, Zhang F, Westerhout J, Mueller D, Li H, Shi Q, Gant TW, Botham P, Bars R, Piersma A, van Ravenzwaay B, Kramer NI. Najjar A, et al. Arch Toxicol. 2022 Dec;96(12):3407-3419. doi: 10.1007/s00204-022-03356-5. Epub 2022 Sep 5. Arch Toxicol. 2022. PMID: 36063173 Free PMC article.
In vitro to in vivo extrapolation to derive a metabolism factor for estimating the aggregate exposure to salicylic acid after dermal exposure of its esters.
Najjar A, Grégoire S, Nicol B, Natsch A, Golbamaki N, Boisleve F, Irizar A, Wall B, Swinscoe A, Masini-Etévé V, Selechnik D, Api AM, Griem P, Hewitt N, Cardamone E. Najjar A, et al. Arch Toxicol. 2024 Apr 24. doi: 10.1007/s00204-024-03749-8. Online ahead of print. Arch Toxicol. 2024. PMID: 38658404
265 results