Laham-Karam N - Search Results

1

Caridac vein retroinjections provide an efficient approach for global left ventricular gene transfer with adenovirus and adeno-associated virus.

Lampela J, Pajula J, Järveläinen N, Siimes S, Laham-Karam N, Kivelä A, Mushimiyimana I, Nurro J, Hartikainen J, Ylä-Herttuala S. Lampela J, et al. Among authors: laham karam n. Sci Rep. 2024 Jan 17;14(1):1467. doi: 10.1038/s41598-024-51712-5. Sci Rep. 2024. PMID: 38233585 Free PMC article.

2

Bile-duct proliferation as an unexpected side-effect after AAV2-LDLR gene transfer to rabbit liver.

Hytönen E, Laurema A, Kankkonen H, Miyanohara A, Kärjä V, Hujo M, Laham-Karam N, Ylä-Herttuala S. Hytönen E, et al. Sci Rep. 2019 May 6;9(1):6934. doi: 10.1038/s41598-019-43459-1. Sci Rep. 2019. PMID: 31061510 Free PMC article.

3

Efficacy and safety of myocardial gene transfer of adenovirus, adeno-associated virus and lentivirus vectors in the mouse heart.

Merentie M, Lottonen-Raikaslehto L, Parviainen V, Huusko J, Pikkarainen S, Mendel M, Laham-Karam N, Kärjä V, Rissanen R, Hedman M, Ylä-Herttuala S. Merentie M, et al. Gene Ther. 2016 Mar;23(3):296-305. doi: 10.1038/gt.2015.114. Epub 2015 Dec 24. Gene Ther. 2016. PMID: 26704723

4

Susceptibility to Cardiac Arrhythmias and Sympathetic Nerve Growth in VEGF-B Overexpressing Myocardium.

Lähteenvuo J, Hätinen OP, Kuivanen A, Huusko J, Paananen J, Lähteenvuo M, Nurro J, Hedman M, Hartikainen J, Laham-Karam N, Mäkinen P, Räsänen M, Alitalo K, Rosenzweig A, Ylä-Herttuala S. Lähteenvuo J, et al. Mol Ther. 2020 Jul 8;28(7):1731-1740. doi: 10.1016/j.ymthe.2020.03.011. Epub 2020 Mar 19. Mol Ther. 2020. PMID: 32243833 Free PMC article.

5

Efficacy and Safety of Clinical-Grade Human Vascular Endothelial Growth Factor-D^ΔNΔC Gene Therapy Containing Residual Replication-Competent Adenoviruses.

Leikas AJ, Laham-Karam N, Agtereek E, Peltonen HM, Selander T, Korpisalo P, Holappa L, Hartikainen JEK, Heikura T, Ylä-Herttuala S. Leikas AJ, et al. Hum Gene Ther. 2021 Jul;32(13-14):761-770. doi: 10.1089/hum.2020.299. Epub 2021 Mar 4. Hum Gene Ther. 2021. PMID: 33371775

6

Optimized Protocol for Accurate Titration of Adeno-Associated Virus Vectors.

Suoranta T, Laham-Karam N, Ylä-Herttuala S. Suoranta T, et al. Hum Gene Ther. 2021 Oct;32(19-20):1270-1279. doi: 10.1089/hum.2020.318. Epub 2021 May 6. Hum Gene Ther. 2021. PMID: 33560161

7

BMP2 gene transfer induces pericardial effusion and inflammatory response in the ischemic porcine myocardium.

Pulkkinen HH, Kivistö-Rahnasto A, Korpela H, Heikkilä M, Järveläinen N, Siimes S, Kilpeläinen L, Laham-Karam N, Ylä-Herttuala S, Laakkonen JP. Pulkkinen HH, et al. Among authors: laham karam n. Front Cardiovasc Med. 2023 Nov 3;10:1279613. doi: 10.3389/fcvm.2023.1279613. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 38028463 Free PMC article.

8

Gene Therapeutic Strategies for Peripheral Artery Disease and New Opportunities Provided by Adeno-Associated Virus Vectors.

Khachigian LM, Varcoe RL, Suoranta T, Laham-Karam N, Ylä-Herttuala S. Khachigian LM, et al. Among authors: laham karam n. Arterioscler Thromb Vasc Biol. 2023 Jun;43(6):836-851. doi: 10.1161/ATVBAHA.122.318902. Epub 2023 Apr 27. Arterioscler Thromb Vasc Biol. 2023. PMID: 37128915 Free article. Review.

9

Genomic Landscapes of Noncoding RNAs Regulating VEGFA and VEGFC Expression in Endothelial Cells.

Mushimiyimana I, Tomas Bosch V, Niskanen H, Downes NL, Moreau PR, Hartigan K, Ylä-Herttuala S, Laham-Karam N, Kaikkonen MU. Mushimiyimana I, et al. Mol Cell Biol. 2021 Jun 23;41(7):e0059420. doi: 10.1128/MCB.00594-20. Epub 2021 Jun 23. Mol Cell Biol. 2021. PMID: 33875575 Free PMC article.

10

Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis.

Mushimiyimana I, Niskanen H, Beter M, Laakkonen JP, Kaikkonen MU, Ylä-Herttuala S, Laham-Karam N. Mushimiyimana I, et al. Nucleic Acids Res. 2021 Aug 20;49(14):8078-8096. doi: 10.1093/nar/gkab633. Nucleic Acids Res. 2021. PMID: 34320216 Free PMC article.

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