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Designed allosteric protein logic.
Cell Discov. 2024 Jan 16;10(1):8. doi: 10.1038/s41421-023-00635-y.
Cell Discov. 2024.
PMID: 38228615
Free PMC article.
Segmentation strategy of de novo designed four-helical bundles expands protein oligomerization modalities for cell regulation.
Merljak E, Malovrh B, Jerala R.
Merljak E, et al.
Nat Commun. 2023 Apr 8;14(1):1995. doi: 10.1038/s41467-023-37765-6.
Nat Commun. 2023.
PMID: 37031229
Free PMC article.
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Metal ion-regulated assembly of designed modular protein cages.
Aupič J, Lapenta F, Strmšek Ž, Merljak E, Plaper T, Jerala R.
Aupič J, et al. Among authors: merljak e.
Sci Adv. 2022 Jun 17;8(24):eabm8243. doi: 10.1126/sciadv.abm8243. Epub 2022 Jun 17.
Sci Adv. 2022.
PMID: 35714197
Free PMC article.
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A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells.
Lebar T, Lainšček D, Merljak E, Aupič J, Jerala R.
Lebar T, et al. Among authors: merljak e.
Nat Chem Biol. 2020 May;16(5):513-519. doi: 10.1038/s41589-019-0443-y. Epub 2020 Jan 6.
Nat Chem Biol. 2020.
PMID: 31907374
Free PMC article.
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Design of fast proteolysis-based signaling and logic circuits in mammalian cells.
Fink T, Lonzarić J, Praznik A, Plaper T, Merljak E, Leben K, Jerala N, Lebar T, Strmšek Ž, Lapenta F, Benčina M, Jerala R.
Fink T, et al. Among authors: merljak e.
Nat Chem Biol. 2019 Feb;15(2):115-122. doi: 10.1038/s41589-018-0181-6. Epub 2018 Dec 10.
Nat Chem Biol. 2019.
PMID: 30531965
Free PMC article.
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Modulation of Coiled-Coil Dimer Stability through Surface Residues while Preserving Pairing Specificity.
Drobnak I, Gradišar H, Ljubetič A, Merljak E, Jerala R.
Drobnak I, et al. Among authors: merljak e.
J Am Chem Soc. 2017 Jun 21;139(24):8229-8236. doi: 10.1021/jacs.7b01690. Epub 2017 Jun 6.
J Am Chem Soc. 2017.
PMID: 28553984
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