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The short-term toxicity and metabolome of dicyclopentadiene.
van Ravenzwaay B, Kocabas NA, Faulhammer F, Flick B, Giri V, Sperber S, Penman MG, Higgins LG, Kamp H, Rooseboom M. van Ravenzwaay B, et al. Among authors: higgins lg. Toxicol Lett. 2024 Mar;393:57-68. doi: 10.1016/j.toxlet.2024.01.005. Epub 2024 Jan 12. Toxicol Lett. 2024. PMID: 38219808 Free article.
Utility of in vivo metabolomics to support read-across for UVCB substances under REACH.
Kamp H, Kocabas NA, Faulhammer F, Synhaeve N, Rushton E, Flick B, Giri V, Sperber S, Higgins LG, Penman MG, van Ravenzwaay B, Rooseboom M. Kamp H, et al. Among authors: higgins lg. Arch Toxicol. 2024 Mar;98(3):755-768. doi: 10.1007/s00204-023-03638-6. Epub 2024 Jan 24. Arch Toxicol. 2024. PMID: 38265474 Free PMC article.
Kinetics of metabolism of deltamethrin and cis- and trans-permethrin in vitro. Studies using rat and human liver microsomes, isolated rat hepatocytes and rat liver cytosol.
Price RJ, Scott MP, Cantrill C, Higgins LG, Moreau M, Yoon M, Clewell HJ, Creek MR, Osimitz TG, Houston JB, Lake BG. Price RJ, et al. Among authors: higgins lg. Xenobiotica. 2021 Jan;51(1):40-50. doi: 10.1080/00498254.2020.1807075. Epub 2020 Aug 26. Xenobiotica. 2021. PMID: 32757971
Combining In Vivo and Organotypic In Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator.
Nudischer R, Renggli K, Bertinetti-Lapatki C, Hoflack JC, Flint N, Sewing S, Pedersen L, Schadt S, Higgins LG, Vardy A, Lenz B, Gand L, Boess F, Elcombe BM, Hierlemann A, Roth AB. Nudischer R, et al. Among authors: higgins lg. Toxicol Sci. 2020 Aug 1;176(2):329-342. doi: 10.1093/toxsci/kfaa076. Toxicol Sci. 2020. PMID: 32458970
31 results