Zanin-Zhorov A - Search Results

1

ROCK2 regulates microglia proliferation and neuronal survival after traumatic brain injury.

Willis EF, Kim SJ, Chen W, Nyuydzefe M, MacDonald KPA, Zanin-Zhorov A, Ruitenberg MJ, Vukovic J. Willis EF, et al. Among authors: zanin zhorov a. Brain Behav Immun. 2024 Mar;117:181-194. doi: 10.1016/j.bbi.2024.01.004. Epub 2024 Jan 10. Brain Behav Immun. 2024. PMID: 38211634 Free article.

2

Selectivity matters: selective ROCK2 inhibitor ameliorates established liver fibrosis via targeting inflammation, fibrosis, and metabolism.

Zanin-Zhorov A, Chen W, Moretti J, Nyuydzefe MS, Zhorov I, Munshi R, Ghosh M, Serdjebi C, MacDonald K, Blazar BR, Palmer M, Waksal SD. Zanin-Zhorov A, et al. Commun Biol. 2023 Nov 18;6(1):1176. doi: 10.1038/s42003-023-05552-0. Commun Biol. 2023. PMID: 37980369 Free PMC article.

3

ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis.

Nalkurthi C, Schroder WA, Melino M, Irvine KM, Nyuydzefe M, Chen W, Liu J, Teng MWL, Hill GR, Bertolino P, Blazar BR, Miller GC, Clouston AD, Zanin-Zhorov A, MacDonald KPA. Nalkurthi C, et al. Among authors: zanin zhorov a. JHEP Rep. 2021 Oct 6;4(1):100386. doi: 10.1016/j.jhepr.2021.100386. eCollection 2022 Jan. JHEP Rep. 2021. PMID: 34917911 Free PMC article.

4

ROCK2, a critical regulator of immune modulation and fibrosis has emerged as a therapeutic target in chronic graft-versus-host disease.

Zanin-Zhorov A, Blazar BR. Zanin-Zhorov A, et al. Clin Immunol. 2021 Sep;230:108823. doi: 10.1016/j.clim.2021.108823. Epub 2021 Aug 14. Clin Immunol. 2021. PMID: 34400321 Free PMC article. Review.

5

ROCK2 Inhibition With Belumosudil (KD025) for the Treatment of Chronic Graft-Versus-Host Disease.

Jagasia M, Lazaryan A, Bachier CR, Salhotra A, Weisdorf DJ, Zoghi B, Essell J, Green L, Schueller O, Patel J, Zanin-Zhorov A, Weiss JM, Yang Z, Eiznhamer D, Aggarwal SK, Blazar BR, Lee SJ. Jagasia M, et al. Among authors: zanin zhorov a. J Clin Oncol. 2021 Jun 10;39(17):1888-1898. doi: 10.1200/JCO.20.02754. Epub 2021 Apr 20. J Clin Oncol. 2021. PMID: 33877856 Free PMC article. Clinical Trial.

6

Author Correction: Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity.

Zanin-Zhorov A, Kumari S, Hippen KL, Merkel SC, MacMillan ML, Blazar BR, Dustin ML. Zanin-Zhorov A, et al. Sci Rep. 2020 Feb 19;10(1):3317. doi: 10.1038/s41598-020-60485-6. Sci Rep. 2020. PMID: 32076101 Free PMC article.

7

ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells.

Chen W, Nyuydzefe MS, Weiss JM, Zhang J, Waksal SD, Zanin-Zhorov A. Chen W, et al. Among authors: zanin zhorov a. Sci Rep. 2018 Nov 9;8(1):16636. doi: 10.1038/s41598-018-35109-9. Sci Rep. 2018. PMID: 30413785 Free PMC article.

8

The selective ROCK2 inhibitor KD025 reduces IL-17 secretion in human peripheral blood mononuclear cells independent of IL-1 and IL-6.

Tengesdal IW, Kitzenberg D, Li S, Nyuydzefe MS, Chen W, Weiss JM, Zhang J, Waksal SD, Zanin-Zhorov A, Dinarello CA. Tengesdal IW, et al. Among authors: zanin zhorov a. Eur J Immunol. 2018 Oct;48(10):1679-1686. doi: 10.1002/eji.201847652. Epub 2018 Sep 21. Eur J Immunol. 2018. PMID: 30098001 Free article.

9

Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling.

Zanin-Zhorov A, Cahalon L, Tal G, Margalit R, Lider O, Cohen IR. Zanin-Zhorov A, et al. J Clin Invest. 2018 Jun 1;128(6):2651. doi: 10.1172/JCI121856. Epub 2018 May 7. J Clin Invest. 2018. PMID: 29733295 Free PMC article. No abstract available.

10

Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity.

Zanin-Zhorov A, Kumari S, Hippen KL, Merkel SC, MacMillan ML, Blazar BR, Dustin ML. Zanin-Zhorov A, et al. Sci Rep. 2017 Jun 26;7(1):4258. doi: 10.1038/s41598-017-04053-5. Sci Rep. 2017. PMID: 28652577 Free PMC article.

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