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Post-pandemic memory T cell response to SARS-CoV-2 is durable, broadly targeted, and cross-reactive to the hypermutated BA.2.86 variant.
Nesamari R, Omondi MA, Baguma R, Höft MA, Ngomti A, Nkayi AA, Besethi AS, Magugu SFJ, Mosala P, Walters A, Clark GM, Mennen M, Skelem S, Adriaanse M, Grifoni A, Sette A, Keeton RS, Ntusi NAB, Riou C, Burgers WA. Nesamari R, et al. Among authors: riou c. Cell Host Microbe. 2024 Feb 14;32(2):162-169.e3. doi: 10.1016/j.chom.2023.12.003. Epub 2024 Jan 10. Cell Host Microbe. 2024. PMID: 38211583 Free PMC article.
Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point.
Gray CM, Mlotshwa M, Riou C, Mathebula T, de Assis Rosa D, Mashishi T, Seoighe C, Ngandu N, van Loggerenberg F, Morris L, Mlisana K, Williamson C, Karim SA; CAPRISA 002 Acute Infection Study Team. Gray CM, et al. Among authors: riou c. J Virol. 2009 Jan;83(1):470-8. doi: 10.1128/JVI.01678-08. Epub 2008 Oct 22. J Virol. 2009. PMID: 18945774 Free PMC article.
Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.
van Grevenynghe J, Procopio FA, He Z, Chomont N, Riou C, Zhang Y, Gimmig S, Boucher G, Wilkinson P, Shi Y, Yassine-Diab B, Said EA, Trautmann L, El Far M, Balderas RS, Boulassel MR, Routy JP, Haddad EK, Sekaly RP. van Grevenynghe J, et al. Among authors: riou c. Nat Med. 2008 Mar;14(3):266-74. doi: 10.1038/nm1728. Epub 2008 Mar 2. Nat Med. 2008. PMID: 18311149
Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells.
Riou C, Yassine-Diab B, Van grevenynghe J, Somogyi R, Greller LD, Gagnon D, Gimmig S, Wilkinson P, Shi Y, Cameron MJ, Campos-Gonzalez R, Balderas RS, Kelvin D, Sekaly RP, Haddad EK. Riou C, et al. J Exp Med. 2007 Jan 22;204(1):79-91. doi: 10.1084/jem.20061681. Epub 2006 Dec 26. J Exp Med. 2007. PMID: 17190839 Free PMC article.
Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point.
Burgers WA, Riou C, Mlotshwa M, Maenetje P, de Assis Rosa D, Brenchley J, Mlisana K, Douek DC, Koup R, Roederer M, de Bruyn G, Karim SA, Williamson C, Gray CM; CAPRISA 002 Acute Infection Study Team. Burgers WA, et al. Among authors: riou c. J Immunol. 2009 Apr 15;182(8):4751-61. doi: 10.4049/jimmunol.0803801. J Immunol. 2009. PMID: 19342652 Free PMC article.
Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for cytomegalovirus-specific CD8+ T cells.
Riou C, Treurnicht F, Abrahams MR, Mlisana K, Liu MK, Goonetilleke N, Koup R, Roederer M, Abdool Karim S, de Bruyn G, Williamson C, Gray CM, Burgers WA; CAPRISA 002 Study Team. Riou C, et al. J Immunol. 2012 Oct 15;189(8):3838-47. doi: 10.4049/jimmunol.1201488. Epub 2012 Sep 10. J Immunol. 2012. PMID: 22966086 Free PMC article.
136 results