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Post-pandemic memory T cell response to SARS-CoV-2 is durable, broadly targeted, and cross-reactive to the hypermutated BA.2.86 variant.
Nesamari R, Omondi MA, Baguma R, Höft MA, Ngomti A, Nkayi AA, Besethi AS, Magugu SFJ, Mosala P, Walters A, Clark GM, Mennen M, Skelem S, Adriaanse M, Grifoni A, Sette A, Keeton RS, Ntusi NAB, Riou C, Burgers WA. Nesamari R, et al. Among authors: burgers wa. Cell Host Microbe. 2024 Feb 14;32(2):162-169.e3. doi: 10.1016/j.chom.2023.12.003. Epub 2024 Jan 10. Cell Host Microbe. 2024. PMID: 38211583 Free PMC article.
Viral oncoproteins target the DNA methyltransferases.
Burgers WA, Blanchon L, Pradhan S, de Launoit Y, Kouzarides T, Fuks F. Burgers WA, et al. Oncogene. 2007 Mar 8;26(11):1650-5. doi: 10.1038/sj.onc.1209950. Epub 2006 Sep 18. Oncogene. 2007. PMID: 16983344 Free PMC article.
Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for cytomegalovirus-specific CD8+ T cells.
Riou C, Treurnicht F, Abrahams MR, Mlisana K, Liu MK, Goonetilleke N, Koup R, Roederer M, Abdool Karim S, de Bruyn G, Williamson C, Gray CM, Burgers WA; CAPRISA 002 Study Team. Riou C, et al. Among authors: burgers wa. J Immunol. 2012 Oct 15;189(8):3838-47. doi: 10.4049/jimmunol.1201488. Epub 2012 Sep 10. J Immunol. 2012. PMID: 22966086 Free PMC article.
88 results