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p66ShcA promotes malignant breast cancer phenotypes by alleviating energetic and oxidative stress.
Lewis K, La Selva R, Maldonado E, Annis MG, Najyb O, Cepeda Cañedo E, Totten S, Hébert S, Sabourin V, Mirabelli C, Ciccolini E, Lehuédé C, Choinière L, Russo M, Avizonis D, Park M, St-Pierre J, Kleinman CL, Siegel PM, Ursini-Siegel J. Lewis K, et al. Among authors: park m. Redox Biol. 2024 Apr;70:103028. doi: 10.1016/j.redox.2024.103028. Epub 2024 Jan 5. Redox Biol. 2024. PMID: 38211442 Free PMC article.
Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response.
Ursini-Siegel J, Cory S, Zuo D, Hardy WR, Rexhepaj E, Lam S, Schade B, Jirstrom K, Bjur E, Piccirillo CA, Denardo D, Coussens LM, Brennan DJ, Gallagher WM, Park M, Pawson T, Hallett M, Muller WJ. Ursini-Siegel J, et al. Among authors: park m. Cancer Res. 2010 Oct 15;70(20):7776-87. doi: 10.1158/0008-5472.CAN-10-2229. Epub 2010 Oct 5. Cancer Res. 2010. PMID: 20924104 Free PMC article.
Claudin-2 is selectively enriched in and promotes the formation of breast cancer liver metastases through engagement of integrin complexes.
Tabariès S, Dong Z, Annis MG, Omeroglu A, Pepin F, Ouellet V, Russo C, Hassanain M, Metrakos P, Diaz Z, Basik M, Bertos N, Park M, Guettier C, Adam R, Hallett M, Siegel PM. Tabariès S, et al. Among authors: park m. Oncogene. 2011 Mar 17;30(11):1318-28. doi: 10.1038/onc.2010.518. Epub 2010 Nov 15. Oncogene. 2011. PMID: 21076473
Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.
Fathers KE, Bell ES, Rajadurai CV, Cory S, Zhao H, Mourskaia A, Zuo D, Madore J, Monast A, Mes-Masson AM, Grosset AA, Gaboury L, Hallet M, Siegel P, Park M. Fathers KE, et al. Among authors: park m. Breast Cancer Res. 2012 May 8;14(3):R74. doi: 10.1186/bcr3183. Breast Cancer Res. 2012. PMID: 22569336 Free PMC article.
It takes two to tango in the microenvironment!
Ursini-Siegel J, Park M. Ursini-Siegel J, et al. Among authors: park m. Breast Cancer Res. 2013 Mar 12;15(2):102. doi: 10.1186/bcr3388. Breast Cancer Res. 2013. PMID: 23510134 Free PMC article.
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