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First-in-human study of CPL207280, a novel G-protein-coupled receptor 40/free fatty acid receptor 1 agonist, in healthy volunteers after single and multiple administration.
Bazydło-Guzenda K, Jarus-Dziedzic K, Gierczak-Pachulska A, Buda P, Rudzki PJ, Buś-Kwaśnik K, Juszczyk E, Tratkiewicz E, Rabczenko D, Segiet-Święcicka A, Wieczorek M. Bazydło-Guzenda K, et al. Among authors: wieczorek m. Diabetes Obes Metab. 2024 Apr;26(4):1376-1385. doi: 10.1111/dom.15439. Epub 2024 Jan 11. Diabetes Obes Metab. 2024. PMID: 38204407
Preclinical characterization of CPL304110 as a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3 for gastric, bladder, and squamous cell lung cancer.
Popiel D, Stańczak A, Skupińska M, Mikołajczyk A, Stańczak P, Mituła F, Hucz-Kalitowska J, Jastrzębska K, Smuga D, Dominowski J, Delis M, Mulewski K, Pietruś W, Zdżalik-Bielecka D, Dzwonek K, Lamparska-Przybysz M, Yamani A, Olejkowska P, Piórkowska N, Dubiel K, Wieczorek M, Pieczykolan J. Popiel D, et al. Among authors: wieczorek m. Front Oncol. 2024 Jan 12;13:1293728. doi: 10.3389/fonc.2023.1293728. eCollection 2023. Front Oncol. 2024. PMID: 38282676 Free PMC article.
The design of experiments (DoE) in optimization of an aerobic flow Pd-catalyzed oxidation of alcohol towards an important aldehyde precursor in the synthesis of phosphatidylinositide 3-kinase inhibitor (CPL302415).
Michałek S, Gurba-Bryśkiewicz L, Maruszak W, Zagozda M, Maj AM, Ochal Z, Dubiel K, Wieczorek M. Michałek S, et al. Among authors: wieczorek m. RSC Adv. 2022 Nov 23;12(52):33605-33611. doi: 10.1039/d2ra07003k. eCollection 2022 Nov 22. RSC Adv. 2022. PMID: 36505705 Free PMC article.
Association Between Visual Acuity and Prospective Fall Risk in Generally Healthy and Active Older Adults: The 3-Year DO-HEALTH Study.
Wieczorek M, Isler M, Landau K, Becker MD, Dawson-Hughes B, Kressig RW, Vellas B, Orav EJ, Rizzoli R, Kanis JA, Armbrecht G, Da Silva JAP, Egli A, Freystätter G, Bischoff-Ferrari HA; DO-HEALTH Research group. Wieczorek M, et al. J Am Med Dir Assoc. 2024 May;25(5):789-795.e2. doi: 10.1016/j.jamda.2024.03.005. Epub 2024 Apr 16. J Am Med Dir Assoc. 2024. PMID: 38640962 Free article. Clinical Trial.
CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC.
Rai D, Song Y, Hua S, Stecker K, Monster JL, Yin V, Stucchi R, Xu Y, Zhang Y, Chen F, Katrukha EA, Altelaar M, Heck AJR, Wieczorek M, Jiang K, Akhmanova A. Rai D, et al. Among authors: wieczorek m. Nat Cell Biol. 2024 Mar;26(3):404-420. doi: 10.1038/s41556-024-01366-2. Epub 2024 Feb 29. Nat Cell Biol. 2024. PMID: 38424271 Free PMC article.
554 results