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SAK/PLK4 is required for centriole duplication and flagella development.
Bettencourt-Dias M, Rodrigues-Martins A, Carpenter L, Riparbelli M, Lehmann L, Gatt MK, Carmo N, Balloux F, Callaini G, Glover DM. Bettencourt-Dias M, et al. Curr Biol. 2005 Dec 20;15(24):2199-207. doi: 10.1016/j.cub.2005.11.042. Epub 2005 Dec 1. Curr Biol. 2005. PMID: 16326102 Free article.
Regulation of autophosphorylation controls PLK4 self-destruction and centriole number.
Cunha-Ferreira I, Bento I, Pimenta-Marques A, Jana SC, Lince-Faria M, Duarte P, Borrego-Pinto J, Gilberto S, Amado T, Brito D, Rodrigues-Martins A, Debski J, Dzhindzhev N, Bettencourt-Dias M. Cunha-Ferreira I, et al. Curr Biol. 2013 Nov 18;23(22):2245-2254. doi: 10.1016/j.cub.2013.09.037. Epub 2013 Oct 31. Curr Biol. 2013. PMID: 24184099 Free article.
PLK4 trans-Autoactivation Controls Centriole Biogenesis in Space.
Lopes CA, Jana SC, Cunha-Ferreira I, Zitouni S, Bento I, Duarte P, Gilberto S, Freixo F, Guerrero A, Francia M, Lince-Faria M, Carneiro J, Bettencourt-Dias M. Lopes CA, et al. Dev Cell. 2015 Oct 26;35(2):222-35. doi: 10.1016/j.devcel.2015.09.020. Epub 2015 Oct 17. Dev Cell. 2015. PMID: 26481051 Free article.
CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis.
Zitouni S, Francia ME, Leal F, Montenegro Gouveia S, Nabais C, Duarte P, Gilberto S, Brito D, Moyer T, Kandels-Lewis S, Ohta M, Kitagawa D, Holland AJ, Karsenti E, Lorca T, Lince-Faria M, Bettencourt-Dias M. Zitouni S, et al. Curr Biol. 2016 May 9;26(9):1127-37. doi: 10.1016/j.cub.2016.03.055. Epub 2016 Apr 21. Curr Biol. 2016. PMID: 27112295 Free PMC article.
Maintaining centrosomes and cilia.
Werner S, Pimenta-Marques A, Bettencourt-Dias M. Werner S, et al. J Cell Sci. 2017 Nov 15;130(22):3789-3800. doi: 10.1242/jcs.203505. J Cell Sci. 2017. PMID: 29142065 Review.
63 results