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TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction.
Griffin PT, Kane AE, Trapp A, Li J, Arnold M, Poganik JR, Conway RJ, McNamara MS, Meer MV, Hoffman N, Amorim JA, Tian X, MacArthur MR, Mitchell SJ, Mueller AL, Carmody C, Vera DL, Kerepesi C, Ying K, Noren Hooten N, Mitchell JR, Evans MK, Gladyshev VN, Sinclair DA. Griffin PT, et al. Among authors: gladyshev vn. Nat Aging. 2024 Feb;4(2):261-274. doi: 10.1038/s43587-023-00555-2. Epub 2024 Jan 10. Nat Aging. 2024. PMID: 38200273
Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan.
Patrick A, Seluanov M, Hwang C, Tam J, Khan T, Morgenstern A, Wiener L, Vazquez JM, Zafar H, Wen R, Muratkalyeva M, Doerig K, Zagorulya M, Cole L, Catalano S, Lobo Ladd AA, Coppi AA, Coşkun Y, Tian X, Ablaeva J, Nevo E, Gladyshev VN, Zhang ZD, Vijg J, Seluanov A, Gorbunova V. Patrick A, et al. Among authors: gladyshev vn. Aging (Albany NY). 2016 May;8(5):841-7. doi: 10.18632/aging.100958. Aging (Albany NY). 2016. PMID: 27163160 Free PMC article.
A whole lifespan mouse multi-tissue DNA methylation clock.
Meer MV, Podolskiy DI, Tyshkovskiy A, Gladyshev VN. Meer MV, et al. Among authors: gladyshev vn. Elife. 2018 Nov 14;7:e40675. doi: 10.7554/eLife.40675. Elife. 2018. PMID: 30427307 Free PMC article.
COVID-19 is an emergent disease of aging.
Santesmasses D, Castro JP, Zenin AA, Shindyapina AV, Gerashchenko MV, Zhang B, Kerepesi C, Yim SH, Fedichev PO, Gladyshev VN. Santesmasses D, et al. Among authors: gladyshev vn. Aging Cell. 2020 Oct;19(10):e13230. doi: 10.1111/acel.13230. Epub 2020 Oct 1. Aging Cell. 2020. PMID: 33006233 Free PMC article.
Reprogramming to recover youthful epigenetic information and restore vision.
Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang JH, Zhou S, Hoffmann EM, Karg MM, Schultz MB, Kane AE, Davidsohn N, Korobkina E, Chwalek K, Rajman LA, Church GM, Hochedlinger K, Gladyshev VN, Horvath S, Levine ME, Gregory-Ksander MS, Ksander BR, He Z, Sinclair DA. Lu Y, et al. Among authors: gladyshev vn. Nature. 2020 Dec;588(7836):124-129. doi: 10.1038/s41586-020-2975-4. Epub 2020 Dec 2. Nature. 2020. PMID: 33268865 Free PMC article.
ARDD 2020: from aging mechanisms to interventions.
Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG, Georgievskaya A, Gladyshev VN, Glass DJ, Gorbunova V, de Grey A, He WW, Hoeijmakers J, Hoffmann E, Horvath S, Houtkooper RH, Jensen MK, Jensen MB, Kane A, Kassem M, de Keizer P, Kennedy B, Karsenty G, Lamming DW, Lee KF, MacAulay N, Mamoshina P, Mellon J, Molenaars M, Moskalev A, Mund A, Niedernhofer L, Osborne B, Pak HH, Parkhitko A, Raimundo N, Rando TA, Rasmussen LJ, Reis C, Riedel CG, Franco-Romero A, Schumacher B, Sinclair DA, Suh Y, Taub PR, Toiber D, Treebak JT, Valenzano DR, Verdin E, Vijg J, Young S, Zhang L, Bakula D, Zhavoronkov A, Scheibye-Knudsen M. Mkrtchyan GV, et al. Among authors: gladyshev vn. Aging (Albany NY). 2020 Dec 30;12(24):24484-24503. doi: 10.18632/aging.202454. Epub 2020 Dec 30. Aging (Albany NY). 2020. PMID: 33378272 Free PMC article. Review.
COVID-19 mortality rate in children is U-shaped.
Khera N, Santesmasses D, Kerepesi C, Gladyshev VN. Khera N, et al. Among authors: gladyshev vn. Aging (Albany NY). 2021 Aug 18;13(16):19954-19962. doi: 10.18632/aging.203442. Epub 2021 Aug 18. Aging (Albany NY). 2021. PMID: 34411000 Free PMC article.
Ectopic cervical thymi and no thymic involution until midlife in naked mole rats.
Emmrich S, Tolibzoda Zakusilo F, Trapp A, Zhou X, Zhang Q, Irving EM, Drage MG, Zhang Z, Gladyshev VN, Seluanov A, Gorbunova V. Emmrich S, et al. Among authors: gladyshev vn. Aging Cell. 2021 Oct;20(10):e13477. doi: 10.1111/acel.13477. Epub 2021 Oct 1. Aging Cell. 2021. PMID: 34596321 Free PMC article.
Emerging rejuvenation strategies-Reducing the biological age.
Zhang B, Trapp A, Kerepesi C, Gladyshev VN. Zhang B, et al. Among authors: gladyshev vn. Aging Cell. 2022 Jan;21(1):e13538. doi: 10.1111/acel.13538. Epub 2021 Dec 31. Aging Cell. 2022. PMID: 34972247 Free PMC article. Review.
452 results