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Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity.
Moorlag SJCFM, Folkman L, Ter Horst R, Krausgruber T, Barreca D, Schuster LC, Fife V, Matzaraki V, Li W, Reichl S, Mourits VP, Koeken VACM, de Bree LCJ, Dijkstra H, Lemmers H, van Cranenbroek B, van Rijssen E, Koenen HJPM, Joosten I, Xu CJ, Li Y, Joosten LAB, van Crevel R, Netea MG, Bock C. Moorlag SJCFM, et al. Among authors: li y, li w. Immunity. 2024 Jan 9;57(1):171-187.e14. doi: 10.1016/j.immuni.2023.12.005. Immunity. 2024. PMID: 38198850 Free article.
Differences in Immune Responses in Individuals of Indian and European Origin: Relevance for the COVID-19 Pandemic.
Geckin B, Zoodsma M, Kilic G, Debisarun PA, Rakshit S, Adiga V, Ahmed A, Parthiban C, Kumar NC, D'Souza G, Baltissen MP, Martens JHA, Domínguez-Andrés J, Li Y, Vyakarnam A, Netea MG. Geckin B, et al. Among authors: li y. Microbiol Spectr. 2023 Feb 13;11(2):e0023123. doi: 10.1128/spectrum.00231-23. Online ahead of print. Microbiol Spectr. 2023. PMID: 36779734 Free PMC article.
Targeted plasma proteomics identifies MICA and IL1R1 proteins associated with HIV-1 reservoir size.
Blaauw MJT, Cristina Dos Santos J, Vadaq N, Trypsteen W, van der Heijden W, Groenendijk A, Zhang Z, Li Y, de Mast Q, Netea MG, Joosten LAB, Vandekerckhove L, van der Ven A, Matzaraki V. Blaauw MJT, et al. Among authors: li y. iScience. 2023 Mar 22;26(4):106486. doi: 10.1016/j.isci.2023.106486. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091231 Free PMC article.
A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity.
Li W, Moorlag SJCFM, Koeken VACM, Röring RJ, de Bree LCJ, Mourits VP, Gupta MK, Zhang B, Fu J, Zhang Z, Grondman I, van Meijgaarden KE, Zhou L, Alaswad A, Joosten LAB, van Crevel R, Xu CJ, Netea MG, Li Y. Li W, et al. Among authors: li y. Cell Rep. 2023 May 30;42(5):112487. doi: 10.1016/j.celrep.2023.112487. Epub 2023 May 7. Cell Rep. 2023. PMID: 37155329 Free PMC article.
The impact of BNT162b2 mRNA vaccine on adaptive and innate immune responses.
Föhse K, Geckin B, Zoodsma M, Kilic G, Liu Z, Röring RJ, Overheul GJ, van de Maat J, Bulut O, Hoogerwerf JJ, Ten Oever J, Simonetti E, Schaal H, Adams O, Müller L, Ostermann PN, van de Veerdonk FL, Joosten LAB, Haagmans BL, van Crevel R, van Rij RP, GeurtsvanKessel C, de Jonge MI, Li Y, Domínguez-Andrés J, Netea MG. Föhse K, et al. Among authors: li y. Clin Immunol. 2023 Oct;255:109762. doi: 10.1016/j.clim.2023.109762. Epub 2023 Sep 6. Clin Immunol. 2023. PMID: 37673225 Free article.
Identification of novel genetic loci for risk of multiple myeloma by functional annotation.
Macauda A, Briem K, Clay-Gilmour A, Cozen W, Försti A, Giaccherini M, Corradi C, Sainz J, Niazi Y, Ter Horst R, Li Y, Netea MG, Vogel U, Hemminki K, Slager SL, Varkonyi J, Andersen V, Iskierka-Jazdzewska E, Mártinez-Lopez J, Zaucha J, Camp NJ, Rajkumar SV, Druzd-Sitek A, Bhatti P, Chanock SJ, Kumar SK, Subocz E, Mazur G, Landi S, Machiela MJ, Jerez A, Norman AD, Hildebrandt MAT, Kadar K, Berndt SI, Ziv E, Buda G, Nagler A, Dumontet C, Raźny M, Watek M, Butrym A, Grzasko N, Dudzinski M, Rybicka-Ramos M, Matera EL, García-Sanz R, Goldschmidt H, Jamroziak K, Jurczyszyn A, Clavero E, Giles GG, Pelosini M, Zawirska D, Kruszewski M, Marques H, Haastrup E, Sánchez-Maldonado JM, Bertsch U, Rymko M, Raab MS, Brown EE, Hofmann JN, Vachon C, Campa D, Canzian F. Macauda A, et al. Among authors: li y. Leukemia. 2023 Nov;37(11):2326-2329. doi: 10.1038/s41375-023-02022-8. Epub 2023 Sep 18. Leukemia. 2023. PMID: 37723249 Free PMC article. No abstract available.
11-deoxycortisol positively correlates with T cell immune traits in physiological conditions.
Peng C, Jiang X, Jaeger M, van Houten P, van Herwaarden AE, Koeken VACM, Moorlag SJCFM, Mourits VP, Lemmers H, Dijkstra H, Koenen HJPM, Joosten I, van Cranenbroek B, Li Y, Joosten LAB, Netea MG, Netea-Maier RT, Xu CJ. Peng C, et al. Among authors: li y. EBioMedicine. 2024 Jan;99:104935. doi: 10.1016/j.ebiom.2023.104935. Epub 2023 Dec 21. EBioMedicine. 2024. PMID: 38134621 Free PMC article.
MMR vaccination induces trained immunity via functional and metabolic reprogramming of γδ T cells.
Röring RJ, Debisarun PA, Botey-Bataller J, Suen TK, Bulut Ö, Kilic G, Koeken VA, Sarlea A, Bahrar H, Dijkstra H, Lemmers H, Gössling KL, Rüchel N, Ostermann PN, Müller L, Schaal H, Adams O, Borkhardt A, Ariyurek Y, de Meijer EJ, Kloet SL, Ten Oever J, Placek K, Li Y, Netea MG. Röring RJ, et al. Among authors: li y. J Clin Invest. 2024 Jan 30;134(7):e170848. doi: 10.1172/JCI170848. J Clin Invest. 2024. PMID: 38290093 Free PMC article. Clinical Trial.
Regulation of SOCS3-STAT3 in urate-induced cytokine production in human myeloid cells.
Badii M, Klück V, Gaal O, Cabău G, Hotea I, Nica V, Mirea AM, Bojan A, Zdrenghea M; HINT Consortium; Novakovic B, Merriman TR, Liu Z, Li Y, Xu CJ, Pamfil C, Rednic S, Popp RA, Crişan TO, Joosten LAB. Badii M, et al. Among authors: li y. Joint Bone Spine. 2024 May;91(3):105698. doi: 10.1016/j.jbspin.2024.105698. Epub 2024 Feb 1. Joint Bone Spine. 2024. PMID: 38309518 Free article.
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