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Biomarker changes preceding symptom onset in genetic prion disease.
medRxiv [Preprint]. 2023 Dec 18:2023.12.18.23300042. doi: 10.1101/2023.12.18.23300042.
medRxiv. 2023.
PMID: 38196583
Free PMC article.
Preprint.
Regional variability and genotypic and pharmacodynamic effects on PrP concentration in the CNS.
Mortberg MA, Zhao HT, Reidenbach AG, Gentile JE, Kuhn E, O'Moore J, Dooley PM, Connors TR, Mazur C, Allen SW, Trombetta BA, McManus A, Moore MR, Liu J, Cabin DE, Kordasiewicz HB, Mathews J, Arnold SE, Vallabh SM, Minikel EV.
Mortberg MA, et al.
JCI Insight. 2022 Mar 22;7(6):e156532. doi: 10.1172/jci.insight.156532.
JCI Insight. 2022.
PMID: 35133987
Free PMC article.
Item in Clipboard
Analysis of non-human primate models for evaluating prion disease therapeutic efficacy.
Mortberg MA, Minikel EV, Vallabh SM.
Mortberg MA, et al.
PLoS Pathog. 2022 Aug 22;18(8):e1010728. doi: 10.1371/journal.ppat.1010728. eCollection 2022 Aug.
PLoS Pathog. 2022.
PMID: 35994510
Free PMC article.
Item in Clipboard
Disease stages and therapeutic hypotheses in two decades of neurodegenerative disease clinical trials.
Mortberg MA, Vallabh SM, Minikel EV.
Mortberg MA, et al.
Sci Rep. 2022 Oct 21;12(1):17708. doi: 10.1038/s41598-022-21820-1.
Sci Rep. 2022.
PMID: 36271285
Free PMC article.
Item in Clipboard
A single-cell map of antisense oligonucleotide activity in the brain.
Mortberg MA, Gentile JE, Nadaf N, Vanderburg C, Simmons S, Dubinsky D, Slamin A, Maldonado S, Petersen CL, Jones N, Kordasiewicz HB, Zhao HT, Vallabh SM, Minikel EV.
Mortberg MA, et al.
bioRxiv [Preprint]. 2023 Feb 14:2023.02.14.528473. doi: 10.1101/2023.02.14.528473.
bioRxiv. 2023.
PMID: 36824749
Free PMC article.
Updated.
Preprint.
Item in Clipboard
A single-cell map of antisense oligonucleotide activity in the brain.
Mortberg MA, Gentile JE, Nadaf NM, Vanderburg C, Simmons S, Dubinsky D, Slamin A, Maldonado S, Petersen CL, Jones N, Kordasiewicz HB, Zhao HT, Vallabh SM, Minikel EV.
Mortberg MA, et al.
Nucleic Acids Res. 2023 Aug 11;51(14):7109-7124. doi: 10.1093/nar/gkad371.
Nucleic Acids Res. 2023.
PMID: 37188501
Free PMC article.
Item in Clipboard
Modulation of prion protein expression through cryptic splice site manipulation.
Gentile JE, Corridon TL, Mortberg MA, D'Souza EN, Whiffin N, Minikel EV, Vallabh SM.
Gentile JE, et al. Among authors: mortberg ma.
bioRxiv [Preprint]. 2023 Dec 19:2023.12.19.572439. doi: 10.1101/2023.12.19.572439.
bioRxiv. 2023.
PMID: 38187635
Free PMC article.
Preprint.
Item in Clipboard
Evidence that minocycline treatment confounds the interpretation of neurofilament as a biomarker.
Gentile JE, Heiss C, Corridon TL, Mortberg MA, Fruhwürth S, Guzman K, Grötschel L, Chan K, Herring NC, Janicki T, Nhass R, Sarathy JM, Erickson B, Kunz R, Erickson A, Braun C, Henry KT, Bry L, Arnold SE, Minikel EV, Zetterberg H, Vallabh SM.
Gentile JE, et al. Among authors: mortberg ma.
medRxiv [Preprint]. 2024 May 2:2024.05.01.24306384. doi: 10.1101/2024.05.01.24306384.
medRxiv. 2024.
PMID: 38746398
Free PMC article.
Preprint.
Item in Clipboard
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