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Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes.
Neyton LPA, Sinha P, Sarma A, Mick E, Kalantar K, Chen S, Wu N, Delucchi K, Zhuo H, Bos LDJ, Jauregui A, Gomez A, Hendrickson CM, Kangelaris KN, Leligdowicz A, Liu KD, Matthay MA, Langelier CR, Calfee CS. Neyton LPA, et al. Among authors: leligdowicz a. Am J Respir Crit Care Med. 2024 Apr 1;209(7):805-815. doi: 10.1164/rccm.202308-1328OC. Am J Respir Crit Care Med. 2024. PMID: 38190719
Biological Mechanisms of COVID-19 Acute Respiratory Distress Syndrome.
Matthay MA, Leligdowicz A, Liu KD. Matthay MA, et al. Among authors: leligdowicz a. Am J Respir Crit Care Med. 2020 Dec 1;202(11):1489-1491. doi: 10.1164/rccm.202009-3629ED. Am J Respir Crit Care Med. 2020. PMID: 32997945 Free PMC article. No abstract available.
Cigarette Smoke Exposure and Acute Respiratory Distress Syndrome in Sepsis: Epidemiology, Clinical Features, and Biologic Markers.
Moazed F, Hendrickson C, Jauregui A, Gotts J, Conroy A, Delucchi K, Zhuo H, Arambulo M, Vessel K, Ke S, Deiss T, Ni A, Leligdowicz A, Abbott J, Cohen MJ, Sinha P, Gomez A, Kangelaris K, Kornblith L, Matthay M, Benowitz N, Liu K, Calfee CS. Moazed F, et al. Among authors: leligdowicz a. Am J Respir Crit Care Med. 2022 Apr 15;205(8):927-935. doi: 10.1164/rccm.202105-1098OC. Am J Respir Crit Care Med. 2022. PMID: 35050845 Free PMC article.
Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults.
Kalantar KL, Neyton L, Abdelghany M, Mick E, Jauregui A, Caldera S, Serpa PH, Ghale R, Albright J, Sarma A, Tsitsiklis A, Leligdowicz A, Christenson SA, Liu K, Kangelaris KN, Hendrickson C, Sinha P, Gomez A, Neff N, Pisco A, Doernberg SB, Derisi JL, Matthay MA, Calfee CS, Langelier CR. Kalantar KL, et al. Among authors: leligdowicz a. Nat Microbiol. 2022 Nov;7(11):1805-1816. doi: 10.1038/s41564-022-01237-2. Epub 2022 Oct 20. Nat Microbiol. 2022. PMID: 36266337 Free PMC article. Clinical Trial.
AIMing Immunomodulation Therapy at Sepsis.
Leligdowicz A, Matthay MA. Leligdowicz A, et al. Am J Respir Cell Mol Biol. 2019 Mar;60(3):253-254. doi: 10.1165/rcmb.2018-0338ED. Am J Respir Cell Mol Biol. 2019. PMID: 30365342 No abstract available.
A neutrophil subset defined by intracellular olfactomedin 4 is associated with mortality in sepsis.
Kangelaris KN, Clemens R, Fang X, Jauregui A, Liu T, Vessel K, Deiss T, Sinha P, Leligdowicz A, Liu KD, Zhuo H, Alder MN, Wong HR, Calfee CS, Lowell C, Matthay MA. Kangelaris KN, et al. Among authors: leligdowicz a. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L892-L902. doi: 10.1152/ajplung.00090.2020. Epub 2020 Dec 23. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33355521 Free PMC article. Clinical Trial.
COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and is modified by dexamethasone.
Sarma A, Christenson SA, Mick E, DeVoe C, Deiss T, Pisco AO, Ghale R, Jauregui A, Byrne A, Moazed F, Spottiswoode N, Sinha P, Zha BS, Neff N, Tan M, Serpa PH, Ansel KM, Wilson JG, Leligdowicz A, Siegel ER, Sirota M, DeRisi JL, Matthay MA; COMET Consortium; Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Calfee CS, Langelier CR. Sarma A, et al. Among authors: leligdowicz a. Res Sq [Preprint]. 2021 Jan 14:rs.3.rs-141578. doi: 10.21203/rs.3.rs-141578/v1. Res Sq. 2021. PMID: 33469573 Free PMC article. Updated. Preprint.
Latent class analysis-derived subphenotypes are generalisable to observational cohorts of acute respiratory distress syndrome: a prospective study.
Sinha P, Delucchi KL, Chen Y, Zhuo H, Abbott J, Wang C, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Calfee CS. Sinha P, et al. Among authors: leligdowicz a. Thorax. 2022 Jan;77(1):13-21. doi: 10.1136/thoraxjnl-2021-217158. Epub 2021 Jul 12. Thorax. 2022. PMID: 34253679 Free PMC article.
97 results