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Targeting CXCR4, VLA-4, and CXCR2 for hematopoietic stem cell mobilization.
Cancilla D, Rettig MP, Karpova D, Thakellapalli H, Singh M, Meyers MJ, Ruminski PG, Christ S, Chendamarai E, Gao F, Gehrs L, Ritchey JK, Prinsen M, DiPersio JF. Cancilla D, et al. Among authors: ritchey jk. Blood Adv. 2024 Mar 26;8(6):1379-1383. doi: 10.1182/bloodadvances.2023011653. Blood Adv. 2024. PMID: 38190608 Free PMC article. No abstract available.
Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37+ lymphoid malignancies.
Frigault MJ, Graham CE, Berger TR, Ritchey JK, Horick N, El-Jawahri A, Scarfò I, Schmidts A, Haradhvala N, Wehrli M, Lee WH, Parker A, Wiggin HR, Bouffard AA, Dey A, Leick MB, Katsis K, Elder EL, Dolaher M, Cook D, Chekmasova AA, Huang L, Nikiforow S, Daley H, Ritz J, Armant M, Preffer F, DiPersio JF, Nardi V, Chen YB, Gallagher KME, Maus MV. Frigault MJ, et al. Among authors: ritchey jk. Blood. 2024 May 23:blood.2024024104. doi: 10.1182/blood.2024024104. Online ahead of print. Blood. 2024. PMID: 38781564
An "off-the-shelf" CD2 universal CAR-T therapy for T-cell malignancies.
Xiang J, Devenport JM, Carter AJ, Staser KW, Kim MY, O' Neal J, Ritchey JK, Rettig MP, Gao F, Rettig G, Turk R, Lee BH, Cooper ML, DiPersio JF. Xiang J, et al. Among authors: ritchey jk. Leukemia. 2023 Dec;37(12):2448-2456. doi: 10.1038/s41375-023-02039-z. Epub 2023 Oct 5. Leukemia. 2023. PMID: 37798328 Free PMC article.
Anti-myeloma efficacy of CAR-iNKT is enhanced with a long-acting IL-7, rhIL-7-hyFc.
O'Neal J, Cooper ML, Ritchey JK, Gladney S, Niswonger J, González LS, Street E, Haas GJ, Carter A, Amayta PN, Gao F, Lee BH, Choi D, Berrien-Elliott M, Zhou A, Fehniger TA, Rettig MP, DiPersio JF. O'Neal J, et al. Among authors: ritchey jk. Blood Adv. 2023 Oct 24;7(20):6009-6022. doi: 10.1182/bloodadvances.2023010032. Blood Adv. 2023. PMID: 37399471 Free PMC article.
CS1 CAR-T targeting the distal domain of CS1 (SLAMF7) shows efficacy in high tumor burden myeloma model despite fratricide of CD8+CS1 expressing CAR-T cells.
O'Neal J, Ritchey JK, Cooper ML, Niswonger J, Sofía González L, Street E, Rettig MP, Gladney SW, Gehrs L, Abboud R, Prior JL, Haas GJ, Jayasinghe RG, Ding L, Ghobadi A, Vij R, DiPersio JF. O'Neal J, et al. Among authors: ritchey jk. Leukemia. 2022 Jun;36(6):1625-1634. doi: 10.1038/s41375-022-01559-4. Epub 2022 Apr 14. Leukemia. 2022. PMID: 35422095 Free PMC article.
36 results