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Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome.
Vinnakota JM, Biavasco F, Schwabenland M, Chhatbar C, Adams RC, Erny D, Duquesne S, El Khawanky N, Schmidt D, Fetsch V, Zähringer A, Salié H, Athanassopoulos D, Braun LM, Javorniczky NR, Ho JNHG, Kierdorf K, Marks R, Wäsch R, Simonetta F, Andrieux G, Pfeifer D, Monaco G, Capitini C, Fry TJ, Blank T, Blazar BR, Wagner E, Theobald M, Sommer C, Stelljes M, Reicherts C, Jeibmann A, Schittenhelm J, Monoranu CM, Rosenwald A, Kortüm M, Rasche L, Einsele H, Meyer PT, Brumberg J, Völkl S, Mackensen A, Coras R, von Bergwelt-Baildon M, Albert NL, Bartos LM, Brendel M, Holzgreve A, Mack M, Boerries M, Mackall CL, Duyster J, Henneke P, Priller J, Köhler N, Strübing F, Bengsch B, Ruella M, Subklewe M, von Baumgarten L, Gill S, Prinz M, Zeiser R. Vinnakota JM, et al. Among authors: chhatbar c. Nat Cancer. 2024 May 13. doi: 10.1038/s43018-024-00764-7. Online ahead of print. Nat Cancer. 2024. PMID: 38741011
Multiomic spatial landscape of innate immune cells at human central nervous system borders.
Sankowski R, Süß P, Benkendorff A, Böttcher C, Fernandez-Zapata C, Chhatbar C, Cahueau J, Monaco G, Gasull AD, Khavaran A, Grauvogel J, Scheiwe C, Shah MJ, Heiland DH, Schnell O, Markfeld-Erol F, Kunze M, Zeiser R, Priller J, Prinz M. Sankowski R, et al. Among authors: chhatbar c. Nat Med. 2024 Jan;30(1):186-198. doi: 10.1038/s41591-023-02673-1. Epub 2023 Dec 20. Nat Med. 2024. PMID: 38123840 Free PMC article.
Brain endothelial STING1 activation by Plasmodium-sequestered heme promotes cerebral malaria via type I IFN response.
Pais TF, Ali H, Moreira da Silva J, Duarte N, Neres R, Chhatbar C, Acúrcio RC, Guedes RC, Strano Moraes MC, Costa-Silva B, Kalinke U, Penha-Gonçalves C. Pais TF, et al. Among authors: chhatbar c. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2206327119. doi: 10.1073/pnas.2206327119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037380 Free PMC article.
From shape to contents: heterogeneity of CNS glial cells.
Chhatbar C, Prinz M. Chhatbar C, et al. Acta Neuropathol. 2022 Feb;143(2):123-124. doi: 10.1007/s00401-021-02398-w. Epub 2021 Dec 15. Acta Neuropathol. 2022. PMID: 34910221 Free PMC article. No abstract available.
Selective reconstitution of IFN‑γ gene function in Ncr1+ NK cells is sufficient to control systemic vaccinia virus infection.
Borst K, Flindt S, Blank P, Larsen PK, Chhatbar C, Skerra J, Spanier J, Hirche C, König M, Alanentalo T, Hafner M, Waibler Z, Pfeffer K, Sexl V, Sutter G, Müller W, Graalmann T, Kalinke U. Borst K, et al. Among authors: chhatbar c. PLoS Pathog. 2020 Feb 5;16(2):e1008279. doi: 10.1371/journal.ppat.1008279. eCollection 2020 Feb. PLoS Pathog. 2020. PMID: 32023327 Free PMC article.
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