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TNIK's emerging role in cancer, metabolism, and age-related diseases.
Ewald CY, Pulous FE, Lok SWY, Pun FW, Aliper A, Ren F, Zhavoronkov A. Ewald CY, et al. Among authors: aliper a. Trends Pharmacol Sci. 2024 May 21:S0165-6147(24)00090-7. doi: 10.1016/j.tips.2024.04.010. Online ahead of print. Trends Pharmacol Sci. 2024. PMID: 38777670 Review.
Quantum-assisted fragment-based automated structure generator (QFASG) for small molecule design: an in vitro study.
Evteev S, Ivanenkov Y, Semenov I, Malkov M, Mazaleva O, Bodunov A, Bezrukov D, Sidorenko D, Terentiev V, Malyshev A, Zagribelnyy B, Korzhenevskaya A, Aliper A, Zhavoronkov A. Evteev S, et al. Among authors: aliper a. Front Chem. 2024 Apr 3;12:1382512. doi: 10.3389/fchem.2024.1382512. eCollection 2024. Front Chem. 2024. PMID: 38633987 Free PMC article.
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models.
Ren F, Aliper A, Chen J, Zhao H, Rao S, Kuppe C, Ozerov IV, Zhang M, Witte K, Kruse C, Aladinskiy V, Ivanenkov Y, Polykovskiy D, Fu Y, Babin E, Qiao J, Liang X, Mou Z, Wang H, Pun FW, Ayuso PT, Veviorskiy A, Song D, Liu S, Zhang B, Naumov V, Ding X, Kukharenko A, Izumchenko E, Zhavoronkov A. Ren F, et al. Among authors: aliper a. Nat Biotechnol. 2024 Mar 8. doi: 10.1038/s41587-024-02143-0. Online ahead of print. Nat Biotechnol. 2024. PMID: 38459338
PandaOmics: An AI-Driven Platform for Therapeutic Target and Biomarker Discovery.
Kamya P, Ozerov IV, Pun FW, Tretina K, Fokina T, Chen S, Naumov V, Long X, Lin S, Korzinkin M, Polykovskiy D, Aliper A, Ren F, Zhavoronkov A. Kamya P, et al. Among authors: aliper a. J Chem Inf Model. 2024 Feb 25. doi: 10.1021/acs.jcim.3c01619. Online ahead of print. J Chem Inf Model. 2024. PMID: 38404138
89 results