Biggs D - Search Results

1

Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice.

King A, Reichl P, Metson JS, Parker R, Munro D, Oliveira C, Becker JR, Biggs D, Preece C, Davies B, Chapman JR. King A, et al. Among authors: biggs d. bioRxiv [Preprint]. 2023 Dec 21:2023.12.20.572534. doi: 10.1101/2023.12.20.572534. bioRxiv. 2023. PMID: 38187711 Free PMC article. Preprint.

2

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice.

Davies B, Hatton E, Altemose N, Hussin JG, Pratto F, Zhang G, Hinch AG, Moralli D, Biggs D, Diaz R, Preece C, Li R, Bitoun E, Brick K, Green CM, Camerini-Otero RD, Myers SR, Donnelly P. Davies B, et al. Among authors: biggs d. Nature. 2016 Feb 11;530(7589):171-176. doi: 10.1038/nature16931. Epub 2016 Feb 3. Nature. 2016. PMID: 26840484 Free PMC article.

3

Electroporation and genetic supply of Cas9 increase the generation efficiency of CRISPR/Cas9 knock-in alleles in C57BL/6J mouse zygotes.

Alghadban S, Bouchareb A, Hinch R, Hernandez-Pliego P, Biggs D, Preece C, Davies B. Alghadban S, et al. Among authors: biggs d. Sci Rep. 2020 Oct 21;10(1):17912. doi: 10.1038/s41598-020-74960-7. Sci Rep. 2020. PMID: 33087834 Free PMC article.

4

Replacement of surgical vasectomy through the use of wild-type sterile hybrids.

Preece C, Alghadban S, Bouchareb A, Moralli D, Biggs D, Davies B. Preece C, et al. Among authors: biggs d. Lab Anim (NY). 2021 Feb;50(2):49-52. doi: 10.1038/s41684-020-00692-w. Epub 2021 Jan 4. Lab Anim (NY). 2021. PMID: 33398200 Free PMC article.

5

Targeted Integration of Transgenes at the Mouse Gt(ROSA)26Sor Locus.

Biggs D, Chen CM, Davies B. Biggs D, et al. Methods Mol Biol. 2023;2631:299-323. doi: 10.1007/978-1-0716-2990-1_13. Methods Mol Biol. 2023. PMID: 36995674

6

Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice.

Davies B, Zhang G, Moralli D, Alghadban S, Biggs D, Preece C, Donnelly P, Hinch AG. Davies B, et al. Among authors: biggs d. Genome Res. 2023 Nov 17;33(11):2018-27. doi: 10.1101/gr.278024.123. Online ahead of print. Genome Res. 2023. PMID: 37977820 Free PMC article.

7

Increasing Knockin Efficiency in Mouse Zygotes by Transient Hypothermia.

Bouchareb A, Biggs D, Alghadban S, Preece C, Davies B. Bouchareb A, et al. Among authors: biggs d. CRISPR J. 2024 Apr;7(2):111-119. doi: 10.1089/crispr.2023.0077. CRISPR J. 2024. PMID: 38635329 Free PMC article.

8

Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.

Hanssen LLP, Kassouf MT, Oudelaar AM, Biggs D, Preece C, Downes DJ, Gosden M, Sharpe JA, Sloane-Stanley JA, Hughes JR, Davies B, Higgs DR. Hanssen LLP, et al. Among authors: biggs d. Nat Cell Biol. 2017 Aug;19(8):952-961. doi: 10.1038/ncb3573. Epub 2017 Jul 24. Nat Cell Biol. 2017. PMID: 28737770 Free PMC article.

9

Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary.

Davies B, Gupta Hinch A, Cebrian-Serrano A, Alghadban S, Becker PW, Biggs D, Hernandez-Pliego P, Preece C, Moralli D, Zhang G, Myers S, Donnelly P. Davies B, et al. Among authors: biggs d. Mol Biol Evol. 2021 Dec 9;38(12):5555-5562. doi: 10.1093/molbev/msab269. Mol Biol Evol. 2021. PMID: 34491357 Free PMC article.

10

A versatile transgenic allele for mouse overexpression studies.

Dolatshad H, Biggs D, Diaz R, Hortin N, Preece C, Davies B. Dolatshad H, et al. Among authors: biggs d. Mamm Genome. 2015 Dec;26(11-12):598-608. doi: 10.1007/s00335-015-9602-y. Epub 2015 Sep 14. Mamm Genome. 2015. PMID: 26369329 Free PMC article.

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