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Vaccine antibodies against a synthetic epidermal growth factor variant enhance the antitumor effects of inhibitors targeting the MAPK/ERK and PI3K/Akt pathways.
García-Roman S, Garzón-Ibáñez M, Bertrán-Alamillo J, Jordana-Ariza N, Giménez-Capitán A, García-Peláez B, Vives-Usano M, Codony-Servat J, d'Hondt E, Rosell R, Molina-Vila MÁ. García-Roman S, et al. Transl Oncol. 2024 Feb;40:101878. doi: 10.1016/j.tranon.2024.101878. Epub 2024 Jan 6. Transl Oncol. 2024. PMID: 38183801 Free PMC article.
Overcoming MET-mediated resistance in oncogene-driven NSCLC.
Reischmann N, Schmelas C, Molina-Vila MÁ, Jordana-Ariza N, Kuntze D, García-Roman S, Simard MA, Musch D, Esdar C, Albers J, Karachaliou N. Reischmann N, et al. Among authors: garcia roman s. iScience. 2023 May 29;26(7):107006. doi: 10.1016/j.isci.2023.107006. eCollection 2023 Jul 21. iScience. 2023. PMID: 37534190 Free PMC article.
The EPICAL trial, a phase Ib study combining first line afatinib with anti-EGF vaccination in EGFR-mutant metastatic NSCLC.
Rodríguez-Abreu D, Cobo M, García-Román S, Viteri-Ramírez S, Jordana-Ariza N, García-Peláez B, Reguart N, Aguilar A, Codony-Servat J, Drozdowskyj A, Molina-Vila MA, d'Hondt E, Rosell R. Rodríguez-Abreu D, et al. Among authors: garcia roman s. Lung Cancer. 2022 Feb;164:8-13. doi: 10.1016/j.lungcan.2021.12.014. Epub 2021 Dec 23. Lung Cancer. 2022. PMID: 34971901 Clinical Trial.
AURKB as a target in non-small cell lung cancer with acquired resistance to anti-EGFR therapy.
Bertran-Alamillo J, Cattan V, Schoumacher M, Codony-Servat J, Giménez-Capitán A, Cantero F, Burbridge M, Rodríguez S, Teixidó C, Roman R, Castellví J, García-Román S, Codony-Servat C, Viteri S, Cardona AF, Karachaliou N, Rosell R, Molina-Vila MA. Bertran-Alamillo J, et al. Among authors: garcia roman s. Nat Commun. 2019 Apr 18;10(1):1812. doi: 10.1038/s41467-019-09734-5. Nat Commun. 2019. PMID: 31000705 Free PMC article.
Prospective analysis of liquid biopsies of advanced non-small cell lung cancer patients after progression to targeted therapies using GeneReader NGS platform.
Mayo de Las Casas C, Garzón-Ibañez M, Jordana-Ariza N, Viteri-Ramírez S, Moya-Horno I, Karachaliou N, Yeste Z, Campos R, Villatoro S, Balada-Bel A, García-Peláez B, Reguart N, Teixidó C, Jantús E, Calabuig S, Aguado C, Giménez-Capitán A, Román-Lladó R, Pérez-Rosado A, Catalán MJ, Bertrán-Alamillo J, García-Román S, Rodriguez S, Alonso L, Aldeguer E, Martínez-Bueno A, González-Cao M, Aguilar Hernandez A, Garcia-Mosquera J, de Los Llanos Gil M, Fernandez M, Rosell R, Molina-Vila MÁ. Mayo de Las Casas C, et al. Among authors: garcia roman s. Transl Cancer Res. 2019 Jan;8(Suppl 1):S3-S15. doi: 10.21037/tcr.2018.10.12. Transl Cancer Res. 2019. PMID: 35117060 Free PMC article.
Anti-Epidermal Growth Factor Vaccine Antibodies Enhance the Efficacy of Tyrosine Kinase Inhibitors and Delay the Emergence of Resistance in EGFR Mutant Lung Cancer Cells.
Codony-Servat J, García-Roman S, Molina-Vila MÁ, Bertran-Alamillo J, Giménez-Capitán A, Viteri S, Cardona AF, D'Hondt E, Karachaliou N, Rosell R. Codony-Servat J, et al. Among authors: garcia roman s. J Thorac Oncol. 2018 Sep;13(9):1324-1337. doi: 10.1016/j.jtho.2018.04.030. Epub 2018 May 8. J Thorac Oncol. 2018. PMID: 29751136 Free article.
Immunotherapy meets targeted therapy: will this team end the war against cancer?
Morales-Espinosa D, García-Román S, Teixidó C, Karachaliou N, Rosell R. Morales-Espinosa D, et al. Among authors: garcia roman s. Transl Lung Cancer Res. 2015 Dec;4(6):752-5. doi: 10.3978/j.issn.2218-6751.2015.12.05. Transl Lung Cancer Res. 2015. PMID: 26798584 Free PMC article. Review.
Pharmacogenomics in the treatment of lung cancer: an update.
Morales-Espinosa D, García-Román S, Karachaliou N, Rosell R. Morales-Espinosa D, et al. Among authors: garcia roman s. Pharmacogenomics. 2015;16(15):1751-60. doi: 10.2217/pgs.15.99. Epub 2015 Oct 2. Pharmacogenomics. 2015. PMID: 26427522 Review.
A critical question for cancer therapy: what new targets exist?
Rosell R, Karachaliou N, Codony J, Teixido C, Garcia-Roman S, Morales D, Cao MG, Viteri S, Veliz I, Loo Y, Castillo O. Rosell R, et al. Among authors: garcia roman s. Transl Lung Cancer Res. 2014 Dec;3(6):384-8. doi: 10.3978/j.issn.2218-6751.2014.08.10. Transl Lung Cancer Res. 2014. PMID: 25806328 Free PMC article.