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Development of new thieno[2,3-d]pyrimidines as dual EGFR and STAT3 inhibitors endowed with anticancer and pro-apoptotic activities.
Bioorg Chem. 2024 Feb;143:107101. doi: 10.1016/j.bioorg.2024.107101. Epub 2024 Jan 4.
Bioorg Chem. 2024.
PMID: 38183682
Novel 4-(2-arylidenehydrazineyl)thienopyrimidine derivatives as anticancer EGFR inhibitors: Design, synthesis, biological evaluation, kinome selectivity and in silico insights.
Elsebaie HA, El-Bastawissy EA, Elberembally KM, Khaleel EF, Badi RM, Shaldam MA, Eldehna WM, Tawfik HO, El-Moselhy TF.
Elsebaie HA, et al.
Bioorg Chem. 2023 Nov;140:106799. doi: 10.1016/j.bioorg.2023.106799. Epub 2023 Aug 22.
Bioorg Chem. 2023.
PMID: 37625210
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