Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

71 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation.
Bravo González-Blas C, Matetovici I, Hillen H, Taskiran II, Vandepoel R, Christiaens V, Sansores-García L, Verboven E, Hulselmans G, Poovathingal S, Demeulemeester J, Psatha N, Mauduit D, Halder G, Aerts S. Bravo González-Blas C, et al. Among authors: christiaens v. Nat Cell Biol. 2024 Jan;26(1):153-167. doi: 10.1038/s41556-023-01316-4. Epub 2024 Jan 5. Nat Cell Biol. 2024. PMID: 38182825 Free PMC article.
cisTopic: cis-regulatory topic modeling on single-cell ATAC-seq data.
Bravo González-Blas C, Minnoye L, Papasokrati D, Aibar S, Hulselmans G, Christiaens V, Davie K, Wouters J, Aerts S. Bravo González-Blas C, et al. Among authors: christiaens v. Nat Methods. 2019 May;16(5):397-400. doi: 10.1038/s41592-019-0367-1. Epub 2019 Apr 8. Nat Methods. 2019. PMID: 30962623 Free PMC article.
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma.
Wouters J, Kalender-Atak Z, Minnoye L, Spanier KI, De Waegeneer M, Bravo González-Blas C, Mauduit D, Davie K, Hulselmans G, Najem A, Dewaele M, Pedri D, Rambow F, Makhzami S, Christiaens V, Ceyssens F, Ghanem G, Marine JC, Poovathingal S, Aerts S. Wouters J, et al. Among authors: christiaens v. Nat Cell Biol. 2020 Aug;22(8):986-998. doi: 10.1038/s41556-020-0547-3. Epub 2020 Aug 3. Nat Cell Biol. 2020. PMID: 32753671
SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks.
Bravo González-Blas C, De Winter S, Hulselmans G, Hecker N, Matetovici I, Christiaens V, Poovathingal S, Wouters J, Aibar S, Aerts S. Bravo González-Blas C, et al. Among authors: christiaens v. Nat Methods. 2023 Sep;20(9):1355-1367. doi: 10.1038/s41592-023-01938-4. Epub 2023 Jul 13. Nat Methods. 2023. PMID: 37443338 Free PMC article.
Cell-type-directed design of synthetic enhancers.
Taskiran II, Spanier KI, Dickmänken H, Kempynck N, Pančíková A, Ekşi EC, Hulselmans G, Ismail JN, Theunis K, Vandepoel R, Christiaens V, Mauduit D, Aerts S. Taskiran II, et al. Among authors: christiaens v. Nature. 2024 Feb;626(7997):212-220. doi: 10.1038/s41586-023-06936-2. Epub 2023 Dec 12. Nature. 2024. PMID: 38086419 Free PMC article.
The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes.
Jacobs J, Atkins M, Davie K, Imrichova H, Romanelli L, Christiaens V, Hulselmans G, Potier D, Wouters J, Taskiran II, Paciello G, González-Blas CB, Koldere D, Aibar S, Halder G, Aerts S. Jacobs J, et al. Among authors: christiaens v. Nat Genet. 2018 Jul;50(7):1011-1020. doi: 10.1038/s41588-018-0140-x. Epub 2018 Jun 4. Nat Genet. 2018. PMID: 29867222 Free PMC article.
A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain.
Davie K, Janssens J, Koldere D, De Waegeneer M, Pech U, Kreft Ł, Aibar S, Makhzami S, Christiaens V, Bravo González-Blas C, Poovathingal S, Hulselmans G, Spanier KI, Moerman T, Vanspauwen B, Geurs S, Voet T, Lammertyn J, Thienpont B, Liu S, Konstantinides N, Fiers M, Verstreken P, Aerts S. Davie K, et al. Among authors: christiaens v. Cell. 2018 Aug 9;174(4):982-998.e20. doi: 10.1016/j.cell.2018.05.057. Epub 2018 Jun 18. Cell. 2018. PMID: 29909982 Free PMC article.
Identification of genomic enhancers through spatial integration of single-cell transcriptomics and epigenomics.
Bravo González-Blas C, Quan XJ, Duran-Romaña R, Taskiran II, Koldere D, Davie K, Christiaens V, Makhzami S, Hulselmans G, de Waegeneer M, Mauduit D, Poovathingal S, Aibar S, Aerts S. Bravo González-Blas C, et al. Among authors: christiaens v. Mol Syst Biol. 2020 May;16(5):e9438. doi: 10.15252/msb.20209438. Mol Syst Biol. 2020. PMID: 32431014 Free PMC article.
Cross-species analysis of enhancer logic using deep learning.
Minnoye L, Taskiran II, Mauduit D, Fazio M, Van Aerschot L, Hulselmans G, Christiaens V, Makhzami S, Seltenhammer M, Karras P, Primot A, Cadieu E, van Rooijen E, Marine JC, Egidy G, Ghanem GE, Zon L, Wouters J, Aerts S. Minnoye L, et al. Among authors: christiaens v. Genome Res. 2020 Dec;30(12):1815-1834. doi: 10.1101/gr.260844.120. Epub 2020 Jul 30. Genome Res. 2020. PMID: 32732264 Free PMC article.
71 results