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Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis.
Venkateswaran N, Garcia R, Lafita-Navarro MC, Hao YH, Perez-Castro L, Nogueira PAS, Solmonson A, Mender I, Kilgore JA, Fang S, Brown IN, Li L, Parks E, Lopes Dos Santos I, Bhaskar M, Kim J, Jia Y, Lemoff A, Grishin NV, Kinch L, Xu L, Williams NS, Shay JW, DeBerardinis RJ, Zhu H, Conacci-Sorrell M. Venkateswaran N, et al. Among authors: kinch l. Nat Commun. 2024 May 20;15(1):4266. doi: 10.1038/s41467-024-47868-3. Nat Commun. 2024. PMID: 38769298 Free PMC article.
The ubiquitin E3 ligase BFAR promotes degradation of PNPLA3.
Das A, Cheng H, Wang Y, Kinch LN, Liang G, Hong S, Hobbs HH, Cohen JC. Das A, et al. Among authors: kinch ln. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2312291121. doi: 10.1073/pnas.2312291121. Epub 2024 Jan 31. Proc Natl Acad Sci U S A. 2024. PMID: 38294943 Free PMC article.
GRB2 is a BECN1 interacting protein that regulates autophagy.
Montero-Vergara J, Plachetta K, Kinch L, Bernhardt S, Kashyap K, Levine B, Thukral L, Vetter M, Thomssen C, Wiemann S, Peña-Llopis S, Jendrossek V, Vega-Rubin-de-Celis S. Montero-Vergara J, et al. Among authors: kinch l. Cell Death Dis. 2024 Jan 5;15(1):14. doi: 10.1038/s41419-023-06387-7. Cell Death Dis. 2024. PMID: 38182563 Free PMC article.
ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells.
Lafita-Navarro MC, Hao YH, Jiang C, Jang S, Chang TC, Brown IN, Venkateswaran N, Maurais E, Stachera W, Zhang Y, Mundy D, Han J, Tran VM, Mettlen M, Xu L, Woodruff JB, Grishin NV, Kinch L, Mendell JT, Buszczak M, Conacci-Sorrell M. Lafita-Navarro MC, et al. Among authors: kinch l. Cell Rep. 2023 Oct 31;42(10):113280. doi: 10.1016/j.celrep.2023.113280. Epub 2023 Oct 16. Cell Rep. 2023. PMID: 37851577 Free PMC article.
152 results